Sulfonyls
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Apexbio Technology LLC Sulfadiazine 68-35-9 5g
Sulfadiazine (CAS 68-35-9) is a small-molecule inhibitor targeting dihydropteroate synthase It is designed to inhibit microbial folate biosynthesis thereby disrupting folic acid synthesis required for pathogen proliferation Sulfadiazine exerts its biological activity primarily through the competitive inhibition of dihydropteroate synthase In in vitro studies Sulfadiazine demonstrates antiparasitic activity with IC50 values ranging from approximately 2 g/mL to 5 g/mL against Toxoplasma gondii depending on experimental conditions and parasite strains Based on these pharmacological properties Sulfadiazine holds research potential in antiparasitic activity evaluation and studies of folic acid metabolism pathways
