Sulfoxides
Medchemexpress LLC 4-(3,4-dihydroisoquinolin-2(1H)-yl)-2-(pyridin-3-yl)quinazoline | 796079-91-9 | 97.0% | 338.41 g/mol | C22H18N4 | 10 MG
GCase modulator-1 (compound 9g) is a quinazoline-derivative small molecule reported to modulate glucocerebrosidase (GCase) activity (reported AC50 = 2.23 μM). It is supplied as a research-grade powder for use in biochemical assays and in vitro studies; reported molecular weight is 338.41 g/mol and reported purity is ~97%.
- Modulates GCase (glucosidase) with reported AC50 = 2.23 μM.
- Quinazoline-derived small-molecule scaffold suitable for biochemical studies.
- Provided as a powder for preparation of assay solutions.
- Reported purity approximately 97% and molecular weight 338.41 g/mol.
- Intended for research use in vitro; not for human or clinical use.
Medchemexpress LLC IL-17 modulator 3 | 2467731-88-8 | >99.5% | 579.73 | 100 MG
IL-17 modulator 3 is an IL-17 modulator (US20200247785A1). IL-17 modulator 3 can be used for the research of inflammation, cancer and autoimmune diseases.
- Functions as an IL-17 modulator
- Supports research in inflammation
- Aids studies related to cancer
- Useful in autoimmune disease research
TARGETMOL CHEMICALS INC GSK2983559 ACTIVE METABO 10MG
Also available in 1 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. GSK2983559 active metabolite (RIPK2-IN-1) is a potent selective receptor-interacting protein-2 (RIP2) kinase inhibitor. purity: 98%
Medchemexpress LLC IL-17A modulator-1 | 2748749-29-1 | 98.8% | C33H31N5O4 | 25 MG
IL-17A modulator-1 is a compound that modulates the activity of IL-17A, an important cytokine involved in immune responses. Derived from patent WO2021239743+A1, this modulator inhibits the biological action of IL-17A with a pIC50 of 8.2, making it suitable for research into various diseases and disorders associated with IL-17A activity, including those with immune components, autoimmune pathologies, cancer, and neurodegenerative disorders. The product is provided as a white to off-white solid.
- Modulates IL-17A activity
- Inhibits biological action of IL-17A
- Suitable for research into immune, autoimmune, cancer, and neurodegenerative disorders
- White to off-white solid appearance
Cayman Chemical AM630 Other Receptor Modulator
An inverse agonist at CB2 and partial agonist at CB1 receptors; binds selectively to CB2 over CB1 receptors (Kis = 31.2 and 5,152 nM, respectively); blocks the antinociceptive effects of cannabinoids; decreases proliferation and induces cell cycle arrest in renal cell carcinoma cells
eMolecules 67-68-5 | Dimethyl Sulfoxide | AA Blocks LLC | MFCD00002089 | 78.130 | C2H6OS | 0.000 | CS(C)=O | 100g | 784389377
Dimethyl Sulfoxide | AA Blocks LLC | 67-68-5 | MFCD00002089 | 78.130 | C2H6OS | 0.000 | CS(C)=O | 100g | 784389377
Medchemexpress LLC NR2F6 modulator-1 | 904449-84-9 | 99.5% | 419.45 | 50 MG
NR2F6 modulator-1 is a potent nuclear receptor subfamily 2, group F, member 6 (NR2F6) modulator. It can be used for researching immune modulation and modulation of cancer stem cell activity.
- Potent nuclear receptor subfamily 2, group F, member 6 (NR2F6) modulator
- Useful for immune modulation research
- Useful for cancer stem cell activity modulation research
- Appearance: solid
- Color: off-white to light yellow
Medchemexpress LLC (+)-LRH-1 modulator-1 | 00-00-0 | 99.4% | C28H36N2O2S | 10MG
(+)-LRH-1 modulator-1 is the (+)-stereoisomer of an LRH-1 modulator and functions as a potent agonist of liver receptor homolog-1 (LRH-1). It modulates inflammatory signaling in intestinal organoid models by inducing IL-10 and reducing IL-1β and TNFα. The compound is provided as a high-purity research-grade small molecule for cellular and biochemical studies of LRH-1 pathways.
- Potent LRH-1 modulator/agonist for receptor pharmacology studies.
- Induces anti-inflammatory cytokine IL-10 in organoid models.
- Reduces proinflammatory cytokines IL-1β and TNFα in assays.
- High purity suitable for cellular and biochemical experiments.
- Available in multiple small-scale quantities for research use.
Medchemexpress LLC Cytochrome P450 27A1 antibody (YA2163) | 100 UL
Cytochrome P450 27A1 Antibody (YA2163) is a rabbit-derived, non-conjugated IgG monoclonal antibody that targets Cytochrome P450 27A1. This enzyme plays a crucial role in cholesterol homeostasis by catalyzing the hydroxylation of cholesterol and its derivatives, leading to bile acid synthesis and modulation of lipid metabolism genes.
- Rabbit-derived monoclonal antibody
- Targets Cytochrome P450 27A1
- Non-conjugated IgG
- Reactive with human, mouse, and rat samples
- Purified by affinity chromatography
- Predicted band size: 60 kDa; Observed band size: 50 kDa
- Suitable for WB, IHC-P, ICC/IF, and FC applications