Sulfoxides
Medchemexpress LLC CB2R/FAAH modulator-3 | 2876918-67-9 | C22H31NO2 | 1 ML
CB2R/FAAH modulator-3 is a dual-targeting modulator that functions as a Cannabinoid receptor 2 (CB2R) agonist and a Fatty Acid Amide Hydrolase (FAAH) inhibitor. This modulator demonstrates a high affinity for CB2R with a Ki value of 20.1 nM, and a lower affinity for CB1R with a Ki value of 67.6 nM. It inhibits FAAH with an IC50 value of 3.4 μM. In in vitro studies, at a concentration of 10 μM, it has been shown to reduce the production of pro-inflammatory cytokines, including TNFα, IFN-γ, IL-1β, and IL6, in unstimulated monocytes and macrophages.
- Suitable for use in research related to various conditions, such as cancer.
- Suitable for use in research related to inflammatory cascades associated with neurodegenerative diseases.
- Suitable for use in research related to COVID-19 infection.
eMolecules Medchem Express / Sulindac sulfide / 50mg / 552386827 / HY-B1786 / / 49627-27-2 / MFCD00869764 / 340.410 / C20H17FO2S
Medchem Express / Sulindac sulfide / 50mg / 552386827 / HY-B1786 / / 49627-27-2 / MFCD00869764 / 340.410 / C20H17FO2S
Cayman Chemical AM630 Other Receptor Modulator
An inverse agonist at CB2 and partial agonist at CB1 receptors; binds selectively to CB2 over CB1 receptors (Kis = 31.2 and 5,152 nM, respectively); blocks the antinociceptive effects of cannabinoids; decreases proliferation and induces cell cycle arrest in renal cell carcinoma cells
TARGETMOL CHEMICALS INC NR2F6 MODULATOR-1 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. NR2F6 modulator-1 is a potent modulator of nuclear receptor subfamily 2 group F member 6 (NR2F6). NR2F6 modulator-1 can be used to study immune regulation and modulation of tumour stem cell activity. purity: 97%
Medchemexpress LLC (E/Z)-Sulindac sulfide | 32004-67-4 | 99.88% | 100 MG
(E/Z)-Sulindac sulfide is a potent γ-secretase modulator (GSM). It selectively reduces Aβ42 production in favor of shorter Aβ species, and it can be used for researching Alzheimer's disease.
- Potent γ-secretase modulator (GSM)
- Selectively reduces Aβ42 production in favor of shorter Aβ species
- Can be used for researching Alzheimer's disease
Medchemexpress LLC MicroRNA modulator-1 | 756865-61-9 | MFCD00050389 | 99.6% | 422.54 g/mol | C21H30N2O5S | 10 MG
MicroRNA modulator-1 is a small-molecule research compound that functions as an oxadiazole miR-21 inhibitor (TABLE4 compound 1) with a reported AC50 of 14.64 μM. It is supplied as a white to off-white powder with high purity and is intended for laboratory research use.
- Oxadiazole miR-21 inhibitor; AC50 14.64 μM.
- White to off-white solid suitable for research applications.
- High purity (≈99.6%).
- Soluble in DMSO (125 mg/mL; sonication-assisted).
- Storage: powder at -20°C; solutions short-term at -20°C, long-term at -80°C.
- Molecular weight 422.54 g/mol; formula C21H30N2O5S.
Medchemexpress LLC Mrgprx2 modulator-1 (example 17) | 2781839-42-5 | 99.0% | 459.39 g/mol | C20H19F6N5O | 10 MG
MRGPRX2 modulator-1 (example 17) is a small-molecule modulator of the Mas-related G-protein coupled receptor X2 (MRGPRX2) supplied for preclinical research. It is intended for studies of inflammation, pain signaling, and autoimmune disorders and is characterized by a confirmed molecular formula, molecular weight, and high HPLC purity.
- Small-molecule modulator of MRGPRX2 suitable for preclinical research.
- High purity (99.03% by HPLC) for consistent bioactivity.
- Molecular formula: C20H19F6N5O; molecular weight: 459.39 g/mol.
- Assigned CAS number 2781839-42-5 for unambiguous identification.
- Provided as a powdered research reagent; handle per SDS instructions.
Medchemexpress LLC DL-sulforaphane glutathione | 289711-21-3 | 484.61 g·mol⁻¹ | C16H28N4O7S3 | 5 MG
DL-Sulforaphane glutathione (DL-SFN-GSH) is the glutathione conjugate metabolite of sulforaphane, reported in rat plasma. It is supplied for research use and commonly used as an analytical reference in metabolic and pharmacokinetic studies to investigate sulforaphane biotransformation.
- Metabolite of sulforaphane identified in vivo.
- Suitable as an analytical standard for metabolic and PK studies.
- Provided in a small research pack for analytical applications.
- Chemical formula C16H28N4O7S3; molecular weight ~484.61 g·mol⁻¹.
- For research use only; not intended for human or clinical use.
TARGETMOL CHEMICALS INC CB2R/FAAH MODULATOR-3 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CB2R/FAAH modulator-3 (compound 27) is a modulator targeting at CB2R and FAAH. CB2R/FAAH modulator-3 acts as a CB2R agonist and FAAH inhibitor the Ki values are 20.1 and 67.6 nM for CB2R and CB1R respectively and the IC50 value for FAAH is 3.4 uM. CB2R/FAAH modulator-3 has research value related to cancer deleterious inflammatory cascades occurring in neurodegenerative diseases and COVID-19 infection. purity: 99%
Medchemexpress LLC GPR120 modulator 2 | 1050506-87-0 | 97.1% | C20H18CINO3S | 50 MG
GPR120 modulator 2 | 1050506-87-0 | 97.1% | C20H18CINO3S | 50 MG