Cinnamic acids and derivatives
Apexbio Technology LLC Tyrphostin 9 10537-47-0 25mg
Tyrphostin 9 is a selective inhibitor targeting platelet-derived growth factor receptor (PDGFR) and epidermal growth factor receptor (EGFR) It inhibits PDGFR autophosphorylation with an IC50 of approximately 2 5 M and EGFR kinase activity (IC50 around 460 M) Additionally Tyrphostin 9 inhibits platelet-derived growth factor (PDGF)-stimulated smooth muscle cell proliferation (IC50 approximately 40 nM) as well as phosphorylation of phospholipase C gamma (PLC IC50 2 5 M) and induction of PDGF-dependent c-fos expression In research models Tyrphostin 9 has been utilized to study receptor-mediated signal transduction and vascular injury-related neointimal proliferation processes
Apexbio Technology LLC Tyrphostin 9 10537-47-0 10mM (in 1mL DMSO)
Tyrphostin 9 is a selective inhibitor targeting platelet-derived growth factor receptor (PDGFR) and epidermal growth factor receptor (EGFR) It inhibits PDGFR autophosphorylation with an IC50 of approximately 2 5 M and EGFR kinase activity (IC50 around 460 M) Additionally Tyrphostin 9 inhibits platelet-derived growth factor (PDGF)-stimulated smooth muscle cell proliferation (IC50 approximately 40 nM) as well as phosphorylation of phospholipase C gamma (PLC IC50 2 5 M) and induction of PDGF-dependent c-fos expression In research models Tyrphostin 9 has been utilized to study receptor-mediated signal transduction and vascular injury-related neointimal proliferation processes
Medchemexpress LLC 2-Methoxycinnamic acid | 6099-03-2 | 178.18 | 1 ML
2-Methoxycinnamic acid is a noncompetitive inhibitor of tyrosinase. It is for research use only.
- Purity: 99.94%
- Appearance: Solid, white to off-white
- Structure classification: Phenylpropanoids, Simple phenylpropanols
- Initial source: Plants (*Pulsatilla chinensis* (Bunge) Regel)
- Solubility (In Vitro): 100 mg/mL (561.23 mM) in DMSO (requires ultrasonication)
- Solubility (In Vivo): ≥ 2.5 mg/mL (14.03 mM) in 10% DMSO, 40% PEG300, 5% Tween-80, 45% Saline (clear solution) or in 10% DMSO, 90% Corn Oil (clear solution)