Cinnamic acids and derivatives
Medchemexpress LLC p-Coumaric acid ethyl ester | 7362-39-2 | MFCD00210460 | 50 MG
p-Coumaric Acid Ethyl Ester is a non-competitive, reversible inhibitor of tyrosinase. It quenches the intrinsic fluorescence of the enzyme and changes the binding affinity of L-tyrosine by inducing conformational changes in the catalytic domain of tyrosinase, without binding to the copper ion of the enzyme. This compound is utilized in the development of medicines, cosmetics, and for fruit preservation.
- Non-competitive, reversible inhibitor of tyrosinase
- Quenches the intrinsic fluorescence of the enzyme
- Induces conformational changes in the catalytic domain of tyrosinase without binding to copper ion
- Exhibits anti-platelet activity in rabbit platelet-rich plasma
- Utilized in medicine and cosmetic development
- Used for fruit preservation
Medchemexpress LLC p-Coumaric Acid Ethyl Ester | 7362-39-2 | 1 ML
p-Coumaric Acid Ethyl Ester, also known as Ethyl (E)-p-hydroxycinnamate or Ethyl trans-4-hydroxycinnamate, is a reversible, non-competitive inhibitor of tyrosinase. It quenches the enzyme's intrinsic fluorescence and alters the binding affinity of L-tyrosine by inducing conformational changes in the catalytic domain, without binding to the copper ion. This compound finds application in the development of various products, including medicines, cosmetics, and fruit preservation products that utilize pollen.
- Non-competitive and reversible tyrosinase inhibitor.
- Changes L-tyrosine binding affinity through conformational changes in tyrosinase's catalytic domain.
- Does not bind to the copper ion of the enzyme.
- Applicable in developing medicines.
- Used in cosmetic formulations.
- Utilized in fruit preservation products.
Medchemexpress LLC p-Coumaric Acid Ethyl Ester | 7362-39-2 | 25 MG
p-Coumaric Acid Ethyl Ester is a non-competitive, reversible inhibitor of tyrosinase, utilized in the development of medicines, cosmetics, and fruit preservation products. It boasts a purity of 99.19% and a molecular weight of 192.21, presenting as a light yellow to light brown solid. This compound also exhibits anti-platelet activity.
- Non-competitive, reversible tyrosinase inhibitor
- IC50 of 4.89 μg/mL and Ki of 1.83 μg/mL against tyrosinase
- Quenches intrinsic fluorescence of the enzyme
- Alters L-tyrosine binding affinity through conformational changes in tyrosinase
- Does not bind to the enzyme's copper ion
- Shows anti-platelet activity in rabbit platelet-rich plasma (IC50 = 130.4 μM)
- Soluble in DMSO at 100 mg/mL
Medchemexpress LLC p-Coumaric Acid Ethyl Ester | 7362-39-2 | 100 MG
p-Coumaric Acid Ethyl Ester is a non-competitive, reversible inhibitor of tyrosinase, used in the development of medicines, cosmetics, and fruit preservation products derived from pollen. It functions by quenching the intrinsic fluorescence of the enzyme and inducing conformational changes in the catalytic domain of tyrosinase, which alters the binding affinity of L-tyrosine without binding to the copper ion.
- Tyrosinase inhibition: Non-competitive, reversible inhibitor with IC50 = 4.89 μg/mL and Ki = 1.83 μg/mL
- Shows anti-platelet activity in rabbit platelet-rich plasma (IC50 = 130.4 μM)
- Used in the development of medicines, cosmetics, and fruit preservation products
- High purity of 99.19%
- Molecular weight: 192.21
- Chemical formula: C11H12O3
- Appearance: Solid, light yellow to light brown
- Soluble in DMSO at 100 mg/mL (520.26 mM)