Flavonoids
TARGETMOL CHEMICALS INC PINOCEMBRIN 25MG
Also available in 5 mg 10 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Pinocembrin (57-Dihydroxyflavanone) is a flavanone a type of flavonoid. It is an antioxidant found in damiana honey fingerroot and propolis. purity: 98%
TARGETMOL CHEMICALS INC AST 487 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. AST 487 (NVP-AST 487) is a RET kinase inhibitor inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3. purity: 99%
Medchemexpress LLC 4H-1-benzopyran-4-one, 2-(4-hydroxyphenyl)- | 4143-63-9 | MFCD00017687 | 97.0% | 238.24 | C15H10O3 | 50 MG
4′-Hydroxyflavone is a flavone derivative supplied as a research-grade chemical for biochemical and pharmacological studies. It inhibits the enzyme aldose reductase (reported IC50 12 μM) and is provided with batch-specific documentation for laboratory use only.
- Inhibits aldose reductase (IC50 = 12 μM).
- High purity: 97.0%.
- Molecular formula C15H10O3; molecular weight 238.24.
- Supplied as a small-molecule reagent for in vitro studies.
- Datasheet and certificate of analysis available.
TARGETMOL CHEMICALS INC Apigenin 200MG
Also available in 1 g, 1 mL, 25 mg, 50 mg, 100 mg, 500 mg and bulk. Please contact Fisher for quotes. Apigenin (NSC 83244) is an aromatic oil extracted from the flowers or leaves of the daisy-like plants. Extracts, oils and teas made from chamomile are used for its soothing qualities as a sedative, mild analgesic and sleep medication. Apigenin has not been implicated in causing serum enzyme elevations or clinically apparent liver injury. Purity 99.66%
![Medchemexpress LLC 5-hydroxy-3-[(2-hydroxyphenyl)methyl]-7-(2-methylnonan-2-yl)chromen-2-one | 1399049-81-0 | 98.0% | 408.53 | C26H32O4 | 10MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000238635.png-250.jpg)
Medchemexpress LLC 5-hydroxy-3-[(2-hydroxyphenyl)methyl]-7-(2-methylnonan-2-yl)chromen-2-one | 1399049-81-0 | 98.0% | 408.53 | C26H32O4 | 10MG
PSB-SB-487 is a coumarin-derived research compound that acts as a potent GPR55 antagonist and CB2 receptor agonist, used in preclinical studies of metabolic disorders, neurodegeneration, neuropathic pain, and cancer. It is supplied for laboratory research in multiple small-mass quantities and includes chemical identifiers and structural data for experimental reproducibility.
- Potent GPR55 antagonist and CB2 agonist.
- Molecular formula C26H32O4 and molecular weight 408.53.
- High purity (98.0%) suitable for research applications.
- Available in small-mass sizes for laboratory experiments.
- Relevant for studies of metabolic disorders, neurodegeneration, pain, and cancer.
- Provided with CAS number and structural identifiers for traceability.
Cayman Chemical Hesperetin Natural Products Ex
A flavonoid with diverse biological activities; reduces ApoB protein levels, ACAT2 expression, and LDL degradation in HepG2 cells from 10-200 µM; inhibits IgG-induced β-hexosaminidase release from RBL-2H3 cells (IC50 = 0.099 mg/ml); inhibits LPS-induced NO production and reduces levels of iNOS, IL-6, and IL-1β in BV-2 microglial cells; inhibits passive cutaneous anaphylaxis in mice at 5 mg/kg; reduces body weight loss, colon shortening, and ulcer severity in a mouse model of TNBS-induced ulcerative colitis; reduces cortical and hippocampal neuronal apoptosis and increases time spent in the target quadrant in the Morris water maze in a mouse model of LPS-induced neuronal inflammation
Medchemexpress LLC Hesperetin 7-O-glucoside | 31712-49-9 | 99.4% | 464.42 g/mol | C22H24O11 | 25MG
Hesperetin 7-O-glucoside is a flavanone monoglucoside used in biochemical and pharmacological research with reported anti-inflammatory and antihypertensive activity. It is suitable for studies of flavonoid metabolism and enzyme inhibition.
- Chemical identity: C22H24O11, CAS 31712-49-9.
- Molecular weight: 464.42 g/mol.
- High purity: 99.4%.
- Reported activities: anti-inflammatory and HMG-CoA reductase inhibition.
- Supplied in small research quantities suitable for assay development and screening.
Selleck Chemical LLC AMG 487
AMG 487 is an orally active and selective CXC chemokine receptor 3 (CXCR3) antagonist that inhibits the binding of IP-10 (CXCL10) and ITAC (CXCL11) to CXCR3 with IC50 of 8 0 nM and 8 2 nM respectively
Apexbio Technology LLC AST 487 630124-46-8 10mM (in 1mL DMSO)
AST487 (CAS 630124-46-8) is a small molecule inhibitor primarily targeting RET kinase exhibiting an IC50 of 0 88 M As a member of the N N -diphenylurea class AST487 inhibits RET autophosphorylation and attenuates downstream signaling pathways such as PLC and ERK in a dose-dependent manner It also displays inhibitory activity against additional kinases including KDR Flt-3 and c-Kit In cellular models harboring RET activating mutations (e g C634W) AST487 suppresses RET-mediated signaling and reduces proliferation of thyroid carcinoma cells with RET mutations In xenograft mouse models oral administration of AST487 leads to a notable reduction in tumor volume making it valuable for preclinical studies of RET-driven cancers
Medchemexpress LLC HY-N1475 5mg Medchemexpress, Nicotiflorin CAS:17650-84-9 Purity:>98%
Medchemexpress, HY-N1475 5mg Nicotiflorin CAS:17650-84-9 Nicotiflorin is a flavonoid glycoside extracted from a traditional Chinese medicine Flos Carthami. Nicotiflorin shows potent antiglycation activity and neuroprotection effects. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.