Isoflavonoids
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Medchemexpress LLC Sophoricoside | 152-95-4 | 432.38 | 1 ML
Sophoricoside is an isoflavone glycoside isolated from *Sophora japonica* with anti-inflammatory, anti-cancer, and immunosuppressive effects. It significantly inhibits histamine release and reduces the levels of TNF-α, IL-8, and IL-6. It also reduces scratching behaviors in vivo and aids in the recovery of atopic dermatitis.
- Inhibits PMACI-induced histamine release
- Reduces TNF-α, IL-8, and IL-6 levels
- Inhibits Rel/p65 nuclear levels
- Reduces caspase-1 activity
- Decreases scratching behaviors in vivo
- Aids in recovery from atopic dermatitis
