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Puerarin is an isoflavone extracted from Pueraria root, functioning as a 5-HT2C receptor antagonist. It inhibits the dorsal motor nucleus of the vagus (DMV)-vagus nerve pathway, which leads to decreased fat absorption.
Acts as a 5-HT2C receptor antagonist
Inhibits LPS-induced iNOS, COX-2, and CRP protein and mRNA expression
Functions as a novel open-channel blocker of IK1
Alleviates hepatic damage from chronic alcohol administration
Improves early-stage renal damage in diabetic rats
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