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Organic compounds that are isomers of flavonoids with a 4-phenylchromen backbone with no hydroxyl group substitution at position 2; also known as phytoestrogens.
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Seratrodast (AA 2414) is an orally active antiasthmatic agent that acts as a thromboxane A2 receptor (TP) antagonist and ferroptosis inhibitor. It reduces lipid ROS production, modulates the systemic xc-/GSH/GPX4 axis, and inhibits JNK phosphorylation and p53 expression. It has demonstrated anti-asthmatic and anti-epileptic activity.
Acts as a thromboxane A2 receptor (TP) antagonist
Functions as a ferroptosis inhibitor
Reduces lipid ROS production
Modulates the systemic xc-/GSH/GPX4 axis
Inhibits JNK phosphorylation and p53 expression
Exhibits anti-asthmatic activity
Exhibits anti-epileptic activity
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