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The alkaline earth metals are beryllium, magnesium, calcium, strontium, barium, and radium. Soft, silvery, and somewhat reactive at standard temperature and pressure, these elements are highly reactive reducing agents that can form ionic halides and oxides.
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Ca2+ channel agonist 1 is an agonist of N-type Ca2+ channel and an inhibitor of Cdk2, with EC50s of 14.23 μM and 3.34 μM, respectively. It is used as a potential treatment for motor nerve terminal dysfunction. For research use only.
Agonist of N-type Ca2+ channel.
Inhibitor of Cdk2.
Potential treatment for motor nerve terminal dysfunction.
Exhibits ca. 2-fold increased agonism and a 22-fold decreased cdk2 kinase activity versus the standard, (R)-roscovitine.
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