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Transition Metals

The transition metals possess partially-filled d sub-shells and are in groups 4 to 11 of the periodic table. They are hard, very conductive, have multiple oxidation states, display catalytic activity, and can form colored and/or paramagnetic compounds.
Iron (Fe) (1)
Ruthenium (Ru) (1)
Yttrium (Y) (1)

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1

Strem, An Ascensus Company CAS 1448663-06-6. 500mg. [13-Bis(26-di-i-propylphenyl)imidazolidin-2-ylidene]2-[[1-(methoxy(methyl)amino)-1-oxopropan-2-yl]oxy]benzylideneruthenium(II) dichloride GreenCat. MFCD28411643
SDP

CAS 1448663-06-6. 500mg. [13-Bis(26-di-i-propylphenyl)imidazolidin-2-ylidene]2-[[1-(methoxy(methyl)amino)-1-oxopropan-2-yl]oxy]benzylideneruthenium(II) dichloride GreenCat. MFCD28411643. Molecular Weight 783.33. Molecular Formula C39H53Cl2N3O3Ru. Color/form green pwdr. Strem 44-0750. http//www.strem.com/catalog/v/44-0750/

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2

eMolecules​ ChemScene / 2-(22-Difluorobenzo[d][13]dioxol-5-yl)ethan-1-amine / 25mg / 714102775 / CS-0200416 / 0.000 / 278183-65-6 / MFCD08449119 / 201.173 / C9H9F2NO2

ChemScene / 2-(22-Difluorobenzo[d][13]dioxol-5-yl)ethan-1-amine / 25mg / 714102775 / CS-0200416 / 0.000 / 278183-65-6 / MFCD08449119 / 201.173 / C9H9F2NO2

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3

Medchemexpress LLC OM-153 | 2406278-81-5 | 99.3% | C28H24FN7O2 | 1 ML
SDP

OM-153 is a potent, orally active tankyrase inhibitor targeting TNKS1/2 with high specificity. It demonstrates strong inhibitory activity against Wnt/β-catenin signaling, which is crucial for cellular proliferation, and has shown antiproliferative effects in COLO 320DM cells.

  • Potently inhibits TNKS1 (IC50: 13 nM) and TNKS2 (IC50: 2 nM).
  • Effectively inhibits Wnt/β-catenin signaling (IC50: 0.63 nM).
  • Exhibits antiproliferative activity in COLO 320DM cells (GI50: 10 nM).
  • Inhibits WNT/β-catenin, YAP, and MYC signaling pathways.
  • Reduces WNT/β-catenin signaling and tumor progression in COLO 320DM xenografts.
  • Potentiates anti-PD-1 immune checkpoint inhibition in melanoma models.

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