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Post-transition metal salts are inorganic, ionic, halogenic compounds in which the heaviest metal atom is a post-transition metal. They are available in a variety of chemical compositions, quantities, purities, and reagent grades.
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Selumetinib (AZD6244) sulfate is a selective, non-ATP-competitive oral MEK1/2 inhibitor. It has an IC50 of 14 nM for MEK1, inhibits ERK1/2 phosphorylation, and can penetrate the blood-brain barrier (BBB).