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Filtered Search Results
Medchemexpress LLC FD-IN-1 | 1646682-14-5 | 98.6% | 10 MG
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FD-IN-1 is an orally bioavailable and selective factor D (FD) inhibitor with an IC50 of 12 nM. This compound targets the alternative complement pathway of the innate immune system, and also exhibits inhibitory activity against factor XIa (FXIa) and Tryptase β2.
- Selective factor D inhibitor (IC50 of 12 nM)
- Inhibits factor XIa (FXIa) and Tryptase β2
- Exhibits high oral bioavailability (83% in mice, 70% in dogs)
- Demonstrates systemic and local ocular suppression of AP activation
- Terminal elimination half-lives of 1.6 hours in mice and 3.8 hours in dogs
- Fully inhibits AP pathway for up to 10 hours at 10 mg/kg dose in human FD knock-in mice
- Molecular weight of 377.43 and chemical formula C23H23NO4
- Appears as a white to off-white solid
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Medchemexpress LLC Acetic acid, 2-[[8-chloro-3-[(4-chlorophenyl)methyl]-4-(difluoromethoxy)-2-ethyl-5-quinolinyl... | 932708-14-0 | 99.4% | 456.27 | 50 MG
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Pexopiprant is an oral antagonist of the prostaglandin D2 receptor 2 (DP2) with a Ki of less than 100 nM. It can be used in studies of asthma.
- Oral antagonist of DP2
- Ki < 100 nM
- Potential use in asthma studies
- For research use only
- Available in solid and solution forms
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Medchemexpress LLC 3-chloro-4,7-difluoro-N-[trans-4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thi | 612542-14-0 | MFCD12032128 | 99.9% | 526.04 | C28H26ClF2N3OS | 25MG
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Hh-Ag1.5 (SAg1.5) is a potent small-molecule agonist of the Hedgehog signaling pathway that activates the Smoothened (Smo) receptor. It is supplied as a white to off-white solid with high reported purity and is used as a research tool to activate Hh signaling in cellular and in vivo studies. The compound is highly soluble in DMSO and has documented storage recommendations for powder and solutions.
- Potent Hedgehog pathway agonist with EC50 ≈ 1 nM.
- Activates Smoothened to induce downstream GLI transcription activity.
- High purity suitable for research (99.9%).
- Soluble in DMSO at 50 mg/mL; in vivo formulations achievable at ≥2.5 mg/mL.
- Stable as powder when stored cold; aliquot solutions to avoid freeze-thaw.
- Demonstrated biological activity in liver stem cell expansion at 5 μM in vitro.
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Strem, An Ascensus Company CAS# 149646-83-3. 100mg. (+)-6,6'-{[(1R,3R)-1,3-Dimethyl-1,3-propanediyl]bis(oxy)}bis[4,8-bis(t-butyl)-2,10-dimethoxy-bibenzo[d,f][1,3,2]dioxaphosphepin], min. 95% (R,R)-Chiraphite. MFCD06798296
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CAS# 149646-83-3. 100mg. (+)-6,6'-{[(1R,3R)-1,3-Dimethyl-1,3-propanediyl]bis(oxy)}bis[4,8-bis(t-butyl)-2,10-dimethoxy-bibenzo[d,f][1,3,2]dioxaphosphepin], min. 95% (R,R)-Chiraphite. MFCD06798296. Molecular Weight: 876.99. Molecular Formula: C49H66O10P2. Color/form: off-white pwdr. Strem# 15-1455. http://www.strem.com/catalog/v/15-1455/
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eMolecules 29876-14-0 | Medchem Express | Nicotredole | 5mg | 552386718 | HY-137394 | MFCD00841846 | 265.316 | C16H15N3O
4-Acetoxybutylzinc bromide | Rieke Metals | 737797-42-1 | 260.440 | C6H11BrO2Zn | [Br-].CC(=O)OCCCC[Zn+] | 50ml | 118909907
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Strem, An Ascensus Company 1kit. DSM MonoPhos™ Ligand Kit.
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1kit. DSM MonoPhos™ Ligand Kit. . Molecular Weight: . Molecular Formula: . Color/form: Strem# 96-5650. http://www.strem.com/catalog/v/96-5650/
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eMolecules 612542-14-0 | Medchem Express | Hh-Ag1.5 | 5mg | 705860454 | HY-124899 | 526.04 | C28H26ClF2N3OS
Medchem Express | Hh-Ag1.5 | 5mg | 705860454 | HY-124899 | 612542-14-0 | 526.040 | C28H26ClF2N3OS
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Apexbio Technology LLC MnTMPyP Pentachloride 125565-45-9 50mg
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MnTMPyP Pentachloride (CAS 125565-45-9) is a manganese (III) porphyrin compound known for superoxide dismutase (SOD) mimetic activity It is designed to catalytically disproportionate superoxide anion radicals into molecular oxygen and hydrogen peroxide thereby modulating intracellular oxidative stress MnTMPyP Pentachloride exerts its biological activity primarily through catalytic scavenging of superoxide radicals In biomedical research MnTMPyP Pentachloride is frequently utilized to investigate cellular redox homeostasis oxidative injury pathways and mechanisms underlying free radical-related signaling events Based on these pharmacological properties MnTMPyP Pentachloride holds research potential in experimental models related to neurological cardiovascular and inflammatory diseases
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Strem, An Ascensus Company BIS(2-DIPHENYLPHOSPHINOPHE-25G
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Bis(2-diphenylphosphinophenyl)ether, 98% DPEphos; Size: 25g; [166330-10-5]; (C6H5)2PC6H4OC6H4P(C6H5)2; Mol Wt:538.56; Color & Form: off-white pwdr.
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eMolecules 126-33-0 | Sulfolane | Oakwood Chemicals | MFCD00005484 | 120.170 | C4H8O2S | 99.000 | O=S1(=O)CCCC1 | 5g | 480131562
Sulfolane | Oakwood Chemicals | 126-33-0 | MFCD00005484 | 120.170 | C4H8O2S | 99.000 | O=S1(=O)CCCC1 | 5g | 480131562
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Strem, An Ascensus Company CAS# 58656-04-5. 1g. Tricyclohexylphosphonium tetrafluoroborate, 99%. MFCD03840580
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CAS# 58656-04-5. 1g. Tricyclohexylphosphonium tetrafluoroborate, 99%. MFCD03840580. Molecular Weight: 368.24. Molecular Formula: [(C6H11)3PH]+BF4ae. Color/form: white pwdr. Strem# 15-6160. http://www.strem.com/catalog/v/15-6160/
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Sigma Aldrich Fine Chemicals Biosciences Phosphorus pentoxide anhydrous, free-flowing, Redi-Dri(TM), ReagentPlus(R), 99% | 1314-56-3 | 1KG
Phosphorus pentoxide anhydrous, free-flowing, Redi-Dri(TM), ReagentPlus(R), 99% | Purity: 99% | Mol Wt: 141.94 | 1314-56-3 | 1KG
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Sigma Aldrich Fine Chemicals Biosciences Phosphorus pentasulfide 99% | 1314-80-3 | MFCD00011441 | 5G
Phosphorus pentasulfide 99% | Purity: 99% | Mol Wt: 222.27 | 1314-80-3 | MFCD00011441 | 5G
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Sigma Aldrich Fine Chemicals Biosciences Phosphorus pentoxide puriss. p.a., ACS reagent, >=98.0% (T) | 1314-56-3 | 500G
Phosphorus pentoxide puriss. p.a., ACS reagent, >=98.0% (T) | Purity: >=98.0% (T) | Mol Wt: 141.94 | 1314-56-3 | 500G
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Sigma Aldrich Fine Chemicals Biosciences Phosphorus pentoxide powder, ACS reagent, >=98.0% | 1314-56-3 | 250G
Phosphorus pentoxide powder, ACS reagent, >=98.0% | Purity: >=98.0% | Mol Wt: 141.94 | 1314-56-3 | 250G
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