Phenols
Medchemexpress LLC ML-00253764 hydrochloride | 1706524-94-8 | 99.29% | 413.71 | 10 MM * 1 ML
ML-00253764 hydrochloride is a brain penetrant nonpeptidic melanocortin receptor 4 (MC4R) antagonist with a Ki and IC50 of 0.16 μM and 0.103 μM, respectively. It can cross the blood-brain barrier.
- Acts as a melanocortin receptor 4 (MC4R) antagonist.
- Crosses the blood-brain barrier.
- Decreases cAMP production in MC4R-expressing HEK293 cell membranes.
- Demonstrates in vivo protection against tumor-induced body weight loss in mouse models.
- Off-white to light yellow solid appearance.
Medchemexpress LLC Upacicalcet (sodium) | 2052969-18-1 | 99.9% | 373.75 | 100 MG
Upacicalcet sodium is a non-peptide calcimimetic that acts as a CaSR agonist (EC50 = 10.8 nM). It reduces serum intact parathyroid hormone (iPTH) and serum Ca2+ levels, thereby reducing hypocalcemia and gastrointestinal complications. It improves vascular calcification and bone disorders in an Adenine-induced secondary hyperparathyroidism (SHPT) rat model, and inhibits cortical pore formation and reduces bone fibrosis in rats with chronic kidney disease (CKD). It is useful for studying SHPT.
- CaSR agonist.
- Reduces iPTH and Ca2+ levels.
- Improves vascular calcification and bone disorders.
- Inhibits cortical pore formation and reduces bone fibrosis.
- Useful for studying SHPT.
Medchemexpress LLC Tropinone | 532-24-1 | MFCD00005549 | 100.0% | 139.20 g/mol | C8H13NO | 100g
Tropinone is an organic synthesis intermediate and a skeleton for constructing derivatives containing thiazole rings and other structures Tropinone derivatives have anticancer activities such as inducing tumor cell apoptosis and inhibiting tyrosinase activity and can be used in research such as anticancer drug development and tyrosinase inhibitor design[1]
Medchemexpress LLC 1,1'-(9,9-dimethyl-9H-xanthene-4,5-diyl)bis(1,1-diphenylphosphine) | 161265-03-8 | MFCD00233866 | 99.9% | 578.62 g/mol | C39H32OP2 | 25g
Xantphos (9 9-Dimethyl-4 5-bis(diphenylphosphino)xanthene) is a bisphosphine ligand Xantphos coordinates to metals in either cis or trans chelation mode Xantphos acts as a key ligand in palladium or platinum catalyzed reactions Xantphos can be used in the construction of heterocyclic compounds in organic synthesis[1][2][3]
Boston Bioproducts Inc Sodium Pyrophosphate (0.2 M) - 2x50ml
Sodium Pyrophosphate (0 2 M) - 2x50ml (For Research Use and Further Manufacturing Only)
BIOHIPPO h/m NRP1-sh-RFP-Puro
h/m NRP1-sh-RFP-Puro shRNA lentiviral vector expressing RFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m NRP1 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse neuropilin 1 (NRP1) The shRNA has been validated to meet or exceed 70% knockdown of NRP1 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
Boston Bioproducts Inc BioAcryl-P Acrylamide/Bis-Acrylamide (30%, 29:1) - 500ml
BioAcryl-P Acrylamide/Bis-Acrylamide (30% 29/1) - 500ml (For Research Use and Further Manufacturing Only)
Boston Bioproducts Inc BioAcryl-P Acrylamide/Bis-Acrylamide (40%, 29:1) - 500ml
BioAcryl-P Acrylamide/Bis-Acrylamide (40% 29/1) - 500ml (For Research Use and Further Manufacturing Only)
TARGETMOL CHEMICALS INC FELCISETRAG 5MG
Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Felcisetrag (TD-8954) is a potent and selective orally active 5-HT4 agonist with gastrointestinal prokinetic properties.Felcisetrag shows high affinity for the human recombinant 5-HT4(c) (h5-HT4(c)) receptor with a pKi of 9.4. purity: 100%
Medchemexpress LLC Potassium sodium L-(+)-tartrate tetrahydrate | 6381-59-5 | MFCD00150989 | 1kg
Rochelle salt is an organic-inorganic compound commonly used as a catalyst and complexing reagent It can be used to catalyze or promote certain chemical reactions and is widely used in batteries pharmaceuticals and food industries In addition this compound is also used as a substrate or intermediate in some biochemical reactions
Medchemexpress LLC 3-(bromomethyl)-2-cyclopropyl-4-(4-fluorophenyl)quinoline | 154057-56-4 | MFCD09031391 | 25g
Pitavastatin impurity 1 is an impurity of Pitavastatin (HY-B0144A)
eMolecules Combi-Blocks TBTU 1kg 267211180 ST-8094 98 000 125700-67-6 MFCD00077413 321 090 C11H16BF4N5O
Combi-Blocks TBTU 1kg 267211180 ST-8094 98 000 125700-67-6 MFCD00077413 321 090 C11H16BF4N5O
![Medchemexpress LLC Benzamide, 2,6-dichloro-4-(cyclopentylamino)-N-[3-(1,1-dimethylethyl)-4-hydroxyphenyl] hydrochloride | 1660153-21-8 | 100.0% | 457.82 g/mol | C22H27Cl3N2O2 | 10 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000285336.png-250.jpg)
Medchemexpress LLC Benzamide, 2,6-dichloro-4-(cyclopentylamino)-N-[3-(1,1-dimethylethyl)-4-hydroxyphenyl] hydrochloride | 1660153-21-8 | 100.0% | 457.82 g/mol | C22H27Cl3N2O2 | 10 MG
FXR Antagonist 2 (hydrochloride) is a diarylamide-derived farnesoid X receptor (FXR) antagonist provided as the hydrochloride salt for research use. It is intended for biochemical and cellular studies of FXR-related signaling and metabolic-disease models. The compound is characterized by a molecular formula C22H27Cl3N2O2, molecular weight 457.82 g/mol, and high HPLC purity as reported on the certificate of analysis.
- High purity suitable for research applications.
- Hydrochloride salt form for improved solubility.
- Diarylamide scaffold useful for FXR antagonism studies.
- Supplied with a certificate of analysis including molecular weight and formula.
- Available in small research pack sizes for assay development.