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Aromatic organic compounds that consist of a phenyl functional group (−C6H5) bonded to a hydroxyl functional group (−OH). Includes compounds with more substitutions and derivatives.
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h/m MCL1 shRNA Set (GFP Puro) shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 (sh-mix) 5x10E6 (scr-mix) transducing units TU Validated human/mouse MCL1 shRNA lentivirus High-titer shRNA lentiviral particles specific for human/mouse MCL1 apoptosis regulator BCL2 family member (MCL1) The shRNA has been validated to meet or exceed 70% MCL1 knockdown efficiency using a specific fluorescence-based method that is more rapid and reliable than qPCR The shRNA lentivirus is ultra-purified and concentrated to high-titer by PEG precipitation and sucrose gradient centrifugation and ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
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h/m FOXA1-sh-GFP-Puro shRNA lentiviral vector expressing GFP with Puromycin selection for studies in Human/Mouse Each vial provides a nominal titer of 5x10E6 transducing units TU Validated h/m FOXA1 shRNA Lentivirus High-titer shRNA lentiviral particles specific for human/mouse forkhead box A1 (FOXA1) The shRNA has been validated to meet or exceed 70% knockdown of FOXA1 using a specific fluorescence-based method that is more rapid and reliable than qPCR The lentiviral particles are ultra-purified and concentrated by PEG precipitation and sucrose gradient centrifugation and are ideal for transducing difficult-to-transfect cells including thawed and/or primary cells Order a shRNA lentivirus set and receive lentivirus produced from mix of 2 independent shRNAs validated to knockdown the target gene ( 70%) plus control lentivirus produced from mix of 2 scrambled shRNA constructs
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A purine derivative that reversibly antagonizes aryl hydrocarbon receptor signaling (IC50 = 127 nM in CD34+ cells); induces a 50-fold increase in human embryonic stem cells expressing CD34 (EC50 = 120 nM) and a 17-fold increase in stem cells that retain the ability to engraft immunodeficient mice
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Also available in 1 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SB-216 is able to be used for the research of cancer which is a potent inhibitor of tubulin polymerization. SB-216 exhibits strong antiproliferative potency in a panel of human cancer cell lines including melanoma breast cancer and lung cancer [1]. purity: 100%
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Galectin-3/LGALS3 protein binds IgE and cooperates with integrins -3 and -1 to promote endothelial cell migration It contributes to epithelial cell differentiation and acts as a splicing factor in the nucleus Galectin-3/LGALS3 Protein Mouse (HEK293 His) is the recombinant mouse-derived Galectin-3/LGALS3 protein expressed by HEK293 with C-His labeled tag
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4-(1-methylethyl)phenyl diphenyl phosphate is an organophosphate flame retardant supplied for research use. Molecular formula C21H21O4P and molecular weight 368.36 g/mol. The material is provided for biochemical assay and research applications; store under the conditions specified in the product Certificate of Analysis.
Organophosphate flame retardant
Intended for research use only
Molecular formula: C21H21O4P
Molecular weight: 368.36 g/mol
CAS number: 55864-04-5
Follow storage conditions in the Certificate of Analysis
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Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. SW033291 is a small-molecule inhibitor of 15-PGDH (Ki=0.1 nM) that increases prostaglandin PGE2 levels in bone marrow and other tissues. purity: 99%
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Also available in 5 mg 10 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. m-3M3FBS is a phospholipase C (PLC) activator. purity: 99%
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Toll-like receptor modulator is a small-molecule research reagent reported to modulate TLR7 and TLR8 signaling and immune responses. Supplied as a light yellow to yellow powder with high reported purity, it is intended for in vitro and in vivo research, and the manufacturer provides stability, storage, and solvent guidance for preparation and dosing.
Modulates TLR7 and TLR8 signaling in immune research.
High reported purity (99.36% by LCMS).
Light yellow to yellow solid form suitable for formulation.
Recommended storage conditions for powder and solutions to maintain stability.
Soluble in DMSO for in vitro use and formulatable for in vivo dosing.
Available in small milligram pack sizes for research applications.
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Mouse IL-23 mRNA encodes a subunit of interleukin-23 (IL-23) IL-23 has two subunits p19 (IL-23 ) and p40 IL-23 binds p40 to form a functional cytokine promoting differentiation and maintenance of Th17 cells which are essential in anti-microbial defense and autoimmune diseases Dysregulated expression of IL-23 is associated with multiple inflammatory diseases such as psoriasis Crohn s disease and multiple sclerosis IL-23 and its subunit IL-23 are therapeutic targets for these diseases and numerous biologics have been developed to inhibit their activity EZ Cap Mouse IL-23 mRNA (m1 HA tag) is provided at 1 mg/mL encoding mouse IL-23 cytokine fused with an HA tag enabling convenient downstream detection of expressed proteins With cap 1 structure generated through co-transcriptional capping incorporation of modified nucleotides m1 along with a poly (A) tail minimizes RNA-induced innate immune activation and enhances mRNA stability and lifespan both in vitro and in vi
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