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Aromatic organic compounds that consist of a phenyl functional group (−C6H5) bonded to a hydroxyl functional group (−OH). Includes compounds with more substitutions and derivatives.
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Cyclobenzaprine HCl (CAS 6202-23-9) is a small molecule antagonist and inhibitor of the 5-HT2 receptor family exhibiting high affinity binding (Ki 62 nM) to 5-HT2 receptors and notably lower affinity for 5-HT1 receptors (Ki 2900 nM) 5-HT2 receptors comprising the 5-HT2A 5-HT2B and 5-HT2C subtypes are G protein-coupled receptors with significant roles in central nervous system signaling Cyclobenzaprine HCl has been shown to suppress both monosynaptic and polysynaptic reflex amplitudes in animal models and reduce neural firing rates suggesting inhibition of spinal reflex transmission through 5-HT2 receptor pathways This compound is utilized in neuroscience research to study serotonergic modulation of synaptic transmission and spinal reflexes
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5'-ODMT cEt N-Bz A Phosphoramidite (Amidite) is a nucleoside phosphoramidite monomer for synthesizing locked nucleic acid (LNA) analog oligonucleotides. It serves as a building block for antisense oligonucleotides (ASOs) to target complementary RNA sequences.
Locks the furanose ring into an N-type conformation through 2',4'-constrained ethyl (cEt) modification
Enhances hybridization affinity and mismatch discrimination with RNA
Significantly improves the resistance of oligonucleotides to exonuclease digestion
Mediates RNase H-dependent mRNA degradation or inhibits translation
Primarily used in the development of antisense drugs, gene function research, and oligonucleotide synthesis
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Solvent Blue 35 (CAS 17354-14-2) is a synthetic lipophilic dye used for selective staining of triglycerides in animal tissue samples It integrates into nonpolar solvents such as alcohols and hydrocarbons to facilitate visualization of neutral lipid components within histological techniques Solvent Blue 35 is applied in laboratory settings for analyzing lipid accumulation distribution and metabolism Based on these properties Solvent Blue 35 holds research potential in the investigation of physiological and pathological lipid storage including fatty liver disease metabolic disorders obesity and related biomedical studies of lipid metabolic pathways
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