Phenols
Apexbio Technology LLC Cyclobenzaprine HCl 6202-23-9 5g
Cyclobenzaprine HCl (CAS 6202-23-9) is a small molecule antagonist and inhibitor of the 5-HT2 receptor family exhibiting high affinity binding (Ki 62 nM) to 5-HT2 receptors and notably lower affinity for 5-HT1 receptors (Ki 2900 nM) 5-HT2 receptors comprising the 5-HT2A 5-HT2B and 5-HT2C subtypes are G protein-coupled receptors with significant roles in central nervous system signaling Cyclobenzaprine HCl has been shown to suppress both monosynaptic and polysynaptic reflex amplitudes in animal models and reduce neural firing rates suggesting inhibition of spinal reflex transmission through 5-HT2 receptor pathways This compound is utilized in neuroscience research to study serotonergic modulation of synaptic transmission and spinal reflexes
Medchemexpress LLC Isovanillin | 621-59-0 | 99.99% | 152.15 | 500 G
Isovanillin is identified as an aldehyde oxidase inhibitor and exhibits antispasmodic and antidiarrheal activities. It is not a substrate for aldehyde oxidase and is metabolized to isovanillic acid primarily by aldehyde dehydrogenase.
- Acts as an aldehyde oxidase inhibitor.
- Demonstrates relaxant effects on ileum contractions induced by 5-HT.
- Has antidiarrheal and anti-motility effects on the gastrointestinal tract.
- Potentially useful for research involving aldehyde oxidase inhibition.
- Offers a compound with known antispasmodic properties for relevant pharmacological studies.
- Provides a substance with documented antidiarrheal effects, suitable for gastrointestinal research.
Chem-Impex International, Inc. Nordihydroguaiaretic acid | MFCD00002206 | 5G
Nordihydroguaiaretic acid, MFCD00002206, 5G