Phenols
Medchemexpress LLC CX-6258 (hydrochloride) | 1353859-00-3 | 99.0% | 498.40 | 1 ML
CX-6258 hydrochloride is a potent and kinase selective pan-Pim kinases inhibitor, with IC50s of 5 nM, 25 nM and 16 nM for Pim-1, Pim-2 and Pim-3, respectively. It is for research use only and not sold to patients.
- Potent and kinase selective pan-Pim kinases inhibitor
- Inhibits Pim-1 with an IC50 of 5 nM, Pim-2 with an IC50 of 25 nM, and Pim-3 with an IC50 of 16 nM
- Causes dose-dependent inhibition of the phosphorylation of pro-survival proteins Bad and 4E-BP1 at specific Pim kinase sites (S112, S65, T37/46)
- Diminishes steady-state levels of ectopic NKX3.1 in PC3 cells and reduces NKX3.1 half-life
- Exhibits robust in vivo efficacy in two Pim kinases driven tumor models, with 50 mg/kg producing 45% tumor growth inhibition (TGI) and 100 mg/kg producing 75% TGI
Medchemexpress LLC Tiviciclovir hydrochloride | 00-00-0 | 275.69 g/mol | C9H14ClN5O3 | 100 MG
Tiviciclovir hydrochloride is an antiviral guanosine analog that inhibits hepatitis B virus replication. Provided for research use only, the compound is supplied as the hydrochloride salt with formula C9H14ClN5O3 and a molecular weight of 275.69 g/mol. Solubility and storage recommendations follow the supplier datasheet.
- Antiviral guanosine analog with HBV inhibitory activity.
- Suitable for in vitro research applications (research use only).
- Soluble in DMSO at 100 mg/mL; may require ultrasonic treatment.
- Stable as a solid when stored sealed at 4°C.
- In solution, store at -80°C for up to 6 months or -20°C for up to 1 month.
- Includes molecular formula and molecular weight for reference.
Medchemexpress LLC N-(4-(2-tert-butylphenyl)sulfonylphenyl)-2,3,4-trihydroxy-5-(2-isopropylbenzyl)benzamide | 877877-35-5 | 99.5% | 1 ML
TW-37 is a small-molecule BH3 mimetic that inhibits anti-apoptotic Bcl-2 family proteins and is used in apoptosis and oncology research. Supplied as a ready-to-use 10 mM solution in DMSO (1 mL), it is intended for research use only.
- Ready-to-use 10 mM solution in DMSO, 1 mL.
- Potent inhibition of Bcl-2 family proteins with Ki values: Mcl-1 260 nM; Bcl-2 290 nM; Bcl-xL 1,110 nM.
- Molecular formula: C33H35NO6S; molecular weight: 573.7 g·mol⁻1.
- High purity (99.5%) suitable for research applications.
- Intended for in vitro research use; not for clinical or therapeutic use.
Medchemexpress LLC CD40L/CD154/TRAP Mo 500ug
CD40L (CD154 TRAP) is a ligand to CD40/TNFRSF5 acts function by generating a costimulatory signal that up-regulates IL-4 synthesis[1] CD40L is specifically expressed on activated CD4 T-lymphocytes and involves in activation of NF- B/MAPK pathway[2][3] CD40L also involves in B cell differentiation maturation and apoptosis[4] CD40L in mouse cleaved into 2 chains of membrane form (1-260 a a ) and soluble form (112-260 a a ) which serves as a ligand for integrins (ITGA5 ITGB1 and ITGAV ITGB3) CD40L/CD154/TRAP Protein Mouse (HEK293 Fc) is expressed in HEK392 cells with N-terminal hFc-tag
eMolecules 402832-76-2 | 2-(2-FLUORO-4-METHOXYPHENYL)ETHANAMINE HCL | MFCD28978585 | 0.25g
Ambeed | ((135-Triazine-246-triyl)tris(benzene-41-diyl))triboronic acid | 100mg | 633660141 | A1271735 | 910231-21-9 | 440.820 | C21H18B3N3O6
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Medchemexpress LLC IL-17A Mouse E. co 50ug
IL-17A protein is an important effector cytokine that activates the NF-kappa-B and MAPkinase pathways through the IL17RA-IL17RC receptor complex to protect host tissues from microbial threats As a key Th17 cytokine IL-17A mediates neutrophil activation chemotaxis and contributes to germinal center formation IL-17A Protein Mouse (E coli) is the recombinant mouse-derived IL-17A protein expressed by E coli with tag free
Medchemexpress LLC IL-17A Mouse E. co 100ug
IL-17A protein is an important effector cytokine that activates the NF-kappa-B and MAPkinase pathways through the IL17RA-IL17RC receptor complex to protect host tissues from microbial threats As a key Th17 cytokine IL-17A mediates neutrophil activation chemotaxis and contributes to germinal center formation IL-17A Protein Mouse (E coli) is the recombinant mouse-derived IL-17A protein expressed by E coli with tag free
Medchemexpress LLC IL-34 Mouse HEK293 10ug
IL-34 protein is an important cytokine that promotes the proliferation survival and differentiation of monocytes and macrophages It plays a key role in innate immune responses and inflammatory processes by promoting the release of pro-inflammatory chemokines IL-34 Protein Mouse (HEK293 His) is the recombinant mouse-derived IL-34 protein expressed by HEK293 with C-His labeled tag
Medchemexpress LLC Alpha-phellandrene | 99-83-2 | 86.7% | 5 G
Alpha-phellandrene (CAS 99-83-2) is a cyclic monoterpene research reagent with reported insecticidal activity. It is a colorless to light yellow liquid (density 0.848 g/cm³) with molecular formula C10H16 and molecular weight 136.23 g/mol.
- High-purity reagent (86.7% typical) suitable for research and analytical applications
- Available in small laboratory quantities, including 5 G
- Soluble in DMSO for solution preparation
- Commonly used in studies of insecticidal activity and essential oil composition
- Store in a cool, well-ventilated place away from heat sources
ABOSYN N-SucciniMidyl 6-[[4-(N-MaleiMidoMethyl)cyclohexyl]carboxaMido]hexanoate, 125559-00-4
N-SucciniMidyl 6-[[4-(N-MaleiMidoMethyl)cyclohexyl]carboxaMido]hexanoate, 125559-00-4
