Aminophylline is a competitive, non-selective phosphodiesterase (PDE) inhibitor and adenosine receptor antagonist. It offers pulmonary vasodilator and bronchodilator actions, aiding asthma research. This dihydrate, a 2:1 ratio compound of theophylline with ethylenediamine, is less potent and shorter-acting than theophylline. It treats airway obstruction in asthma or COPD and serves off-label as a reversal agent during nuclear stress testing.
- Competitive PDE inhibitor and adenosine receptor antagonist
- Exhibits pulmonary vasodilator and bronchodilator actions
- Useful for asthma research
- Composed of theophylline with ethylenediamine (2:1 ratio)
- Less potent and shorter-acting than theophylline
- Treats airway obstruction in asthma or COPD
- Used off-label for nuclear stress test reversal
- Increases heart rate and contractility