Phenols
Apexbio Technology LLC 10058-F4 403811-55-2 10mM (in 1mL DMSO)
10058-F4 (CAS 403811-55-2) is a small molecule inhibitor targeting the transcription factor c-Myc It disrupts the dimerization of c-Myc with Max thereby preventing the c-Myc/Max complex from binding to DNA This disruption impairs c-Myc-dependent transcriptional activity leading to inhibited proliferation and induction of apoptosis in leukemia cells as evidenced by Bcl-2 downregulation Bax upregulation and cytochrome c release 10058-F4 has also been shown to suppress growth factor-induced expression of PGC-1 implicating c-Myc in related transcriptional events Additionally in lymphoma cells it reduces c-Myc mRNA levels The compound is widely used in research to investigate c-Myc function in oncogenesis and cellular metabolism
Medchemexpress LLC Acetaminophen (Standard) | 103-90-2 | 99.97% | C8H9NO2 | 100 MG
Acetaminophen (Standard) is an analytical standard of Acetaminophen, intended for research and analytical applications. Also known as Paracetamol, it acts as a selective cyclooxygenase-2 (COX-2) inhibitor with an IC50 of 25.8 μM, and is widely used as an antipyretic and analgesic agent. It is also a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
- Analytical standard for research and analytical applications.
- Selective cyclooxygenase-2 (COX-2) inhibitor (IC50 of 25.8 μM).
- Widely used antipyretic and analgesic agent.
- Potent hepatic N-acetyltransferase 2 (NAT2) inhibitor.
- Used in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
Medchemexpress LLC 2-(Triphenylphosphoranylidene)acetaldehyde | 2136-75-6 | 99.7% | C20H17OP | 50 G
2-(Triphenylphosphoranylidene)acetaldehyde is a biochemical reagent that can be used as a biological material or organic compound for life science related research. It is also used as a Wittig reagent, pharmaceutical intermediate, and raw material in organic synthesis and agrochemicals.
- Used as a biochemical reagent
- Can be used as a biological material or organic compound
- Suitable for life science related research
- Functions as a Wittig reagent
- Utilized as pharmaceutical intermediates
- Raw material in organic synthesis
- Raw material in agrochemicals
Medchemexpress LLC 5-Bromo-3-methylpyridin-2-ol | 89488-30-2 | 99.7% | C6H6BrNO | 10 G
5-Bromo-3-methylpyridin-2(1H)-one is a biochemical reagent intended for life science research. This compound appears as a white to off-white solid with a molecular weight of 188.02 and a chemical formula of C6H6BrNO.
- High purity for research applications
- Biochemical reagent for life science research
- White to off-white solid appearance
- Stable as powder at -20°C for 3 years or 4°C for 2 years
- Stable in solvent at -80°C for 6 months or -20°C for 1 month
Sigma Aldrich Fine Chemicals Biosciences 2,5-Dihydroxybenzoic acid analytical standard | 490-79-9 | MFCD00002460 | 25MG
2,5-Dihydroxybenzoic acid analytical standard | Purity: >=99.0% (HPLC) | Mol Wt: 154.12 | 490-79-9 | MFCD00002460 | 25MG
Medchemexpress LLC Recombinant Human Serum Albumin (rHSA) | 99.6% | 5 G
Recombinant Human Serum Albumin (rHSA) is a non-glycosylated monomeric plasma protein crucial for maintaining plasma colloid osmotic pressure. It performs various physiological functions, including carrier, metabolic regulation, detoxification, antioxidation, and enzyme mimicking. rHSA helps scavenge reactive oxygen and nitrogen species, binds various compounds to maintain redox homeostasis, and serves as a biomarker for diseases like cancer and inflammation.
- Supports development of implantable materials, surgical adhesives, and ligand capture
- Useful for research on critical illnesses including hypovolemia, liver failure, severe sepsis, and trauma resuscitation
- Non-glycosylated monomeric plasma protein
- Maintains plasma colloid osmotic pressure
- Acts as a carrier and aids metabolic regulation
- Functions in detoxification and antioxidation
- Serves as a biomarker for various diseases
Medchemexpress LLC 2-Hydroxybenzonitrile | 611-20-1 | 99.99% | 119.12 | 25 G
2-Hydroxybenzonitrile is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
- Biochemical reagent
- Biological material
- Organic compound for life science research
- Solid appearance
- Off-white to light yellow color
Apexbio Technology LLC Ro 106-9920 62645-28-7 1mg
Ro 106-9920 (CAS 62645-28-7) is a small molecule inhibitor that selectively suppresses the activation of the NF-kappaB signaling pathway By interfering with NF-kappaB function Ro 106-9920 modulates transcriptional events involved in cellular inflammatory responses survival and tumor progression Aberrant NF-kappaB activity is frequently observed in various cancer cell types and is linked to enhanced proliferation invasion and resistance to apoptosis Ro 106-9920 is widely utilized in cellular and animal studies to investigate the roles of NF-kappaB in oncogenesis and related pathologies providing a valuable tool for elucidating NF-kappaB-mediated mechanisms and evaluating potential therapeutic strategies
Medchemexpress LLC Neurotoxin Inhibitor | 951571-70-3 | 99.0% | 346.41 | 1 ML
Neurotoxin Inhibitor is a neurotoxin inhibitor that promotes the expression of DJ-1 protein, reduces the level of oxidative stress, and thereby protects dopaminergic neurons. It can be used for the study of Parkinson's disease.
- Promotes the expression of DJ-1 protein.
- Reduces the level of oxidative stress.
- Protects dopaminergic neurons.
- Can be used for the study of Parkinson's disease.
- Dose-dependently upregulates the expression of DJ-1 protein in SH-SY5Y cells and primary cortical neurons of mice.
- Effectively alleviates excessive oxidative stress in SH-SY5Y cells treated with MPP⁺.
Apexbio Technology LLC Terazosin HCl 70024-40-7 10mM (in 1mL DMSO)
Terazosin hydrochloride (CAS 70024-40-7) is a selective antagonist of alpha1-adrenergic receptors By inhibiting these receptors terazosin induces relaxation of smooth muscle in the prostate and bladder neck thereby reducing urinary outflow resistance It is widely utilized in biomedical research to study the modulation of alpha1-adrenergic signaling pathways and the pathophysiology of lower urinary tract symptoms particularly in the context of benign prostatic hyperplasia (BPH) Its mechanism supports investigations into autonomic regulation of smooth muscle function and the pharmacological management of urological disorders
Sigma Aldrich Fine Chemicals Biosciences Guaiacol natural, >=99%, FG | 90-05-1 | MFCD00002185 | 5KG
Guaiacol natural, >=99%, FG | Purity: >=99% | Mol Wt: 124.14 | 90-05-1 | MFCD00002185 | 5KG
Apexbio Technology LLC Chlorprothixene (hydrochloride) 6469-93-8 10mM (in 1mL DMSO)
Chlorprothixene hydrochloride (CAS 6469-93-8) is a small-molecule antagonist targeting dopamine (D1 D2 D3 D5) and histamine H1 receptors It modulates neurotransmission by blocking these receptors thereby regulating dopaminergic and histaminergic pathways Chlorprothixene hydrochloride exerts its biological activity primarily through receptor antagonism In in vitro studies it demonstrates nanomolar affinity with Ki values of 18 nM (D1) 2 96 nM (D2) 4 56 nM (D3) 9 nM (D5) and 3 75 nM (H1) Additionally it reduces SARS-CoV viral replication (IC50 13 0 18 5 M depending on strain) Based on these pharmacological properties chlorprothixene hydrochloride holds research potential in antipsychotic therapy antiviral investigation and modulation of inflammation in cystic fibrosis models
Medchemexpress LLC PVA (Mw 145000, 99+% hydrolyzed, ~3300 polymerization) | 9002-89-5 | 99.1% | 145000 | 10 G
PVA (Mw 145000, 99+% hydrolyzed, ~3300 polymerization) is a polyvinyl alcohol with a molecular weight of 145000 with hydrolysis properties. The hydrolysis degree refers to the conversion rate of the acetic acid group hydrolysis to the hydroxyl group in the original polyvinyl acetate. This polyvinyl alcohol is obtained from the polymerization of vinyl acetate to remove the acetic acid group by hydrolysis. Polyvinyl alcohol with different degrees of hydrolysis can be self-crosslinked to form frozen gels and can be used as biological excipients.
- Molecular weight of 145000 (average)
- Possesses hydrolysis properties
- Obtained by polymerizing vinyl acetate
- Can be self-crosslinked to form frozen gels
- Used as biological excipients
- Appears as a white to off-white solid