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Aromatic organic compounds that consist of a phenyl functional group (−C6H5) bonded to a hydroxyl functional group (−OH). Includes compounds with more substitutions and derivatives.
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FTI-277 hydrochloride is an inhibitor of farnesyl transferase (FTase). It is a highly potent Ras CAAX peptidomimetic that antagonizes both H- and K-Ras oncogenic signaling and can inhibit hepatitis delta virus (HDV) infection.
Inhibits farnesyl transferase (FTase)
Antagonizes H- and K-Ras oncogenic signaling
Can inhibit hepatitis delta virus (HDV) infection
Significantly decreases survival of radioresistant cells expressing the 24-kDa isoform
Stimulates postmitotic cell death in HeLa 3A cells
Reduces G(2)/M-phase arrest in both cell types (HeLa 3A and HeLa PINA)
Inhibits migration and invasion in PC-3 cells
Prevents increased PTP-1B and PTEN protein expression in burned mice
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2,4,6-triiodophenol is an iodinated phenol supplied for laboratory research and described as an orally active inhibitor of leukotriene B4 (LTB4) synthesis. It is provided as a solid and has documented biological activity including induction of apoptosis in mouse blastocysts.
cas number: 609-23-4.
chemical formula: C6H3I3O.
molecular weight: 471.80 g/mol.
reported purity: catalog lists 98.0%; batch COA reports 99.52%.
biological activity: LTB4 synthesis inhibitor.
observed effect: can induce apoptosis in mouse blastocysts.
form and packaging: solid powder, supplied in multiple sizes including 100 mg.
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Tempol (4-hydroxy-TEMPO) is a stable nitroxide radical used as a superoxide dismutase (SOD)-mimetic and reactive oxygen species (ROS) scavenger. It is provided as an analytical standard for research and analytical applications and is commonly used in oxidative stress assays, electron spin resonance (ESR) spin-labeling, and chromatographic or mass-spectrometry methods.
Acts as an SOD-mimetic and efficiently scavenges ROS.
Stable, cell-permeable nitroxide suitable for biological studies.
Supplied as an analytical standard for quantitative and qualitative analysis.
Suitable as a spin label for ESR and related spectroscopy techniques.
Applicable in oxidative stress assays, HPLC, GC, and MS workflows.
Documentation available, including safety data and handling instructions.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More