TNP-470 is a synthetic analog of fumagillin that irreversibly inhibits methionine aminopeptidase-2 (MetAP2), blocking endothelial cell proliferation and angiogenesis. It is supplied as a crystalline solid for research use, typically at >98% purity and stored at -20 °C. Common applications include studies of angiogenesis, MetAP2-related signaling, and preclinical evaluation of anti-angiogenic strategies.
- Irreversible MetAP2 inhibitor with anti-angiogenic activity.
- High purity suitable for biochemical and cell-based assays.
- Crystalline solid form for accurate dosing and stability.
- Storage at -20 °C maintains compound integrity.
- Used in vascular biology and cancer research models.