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Organic compounds that contain a carboxyl group bonded to an organic functional group; carboxyl groups consist of a carbonyl group bonded to a hydroxy group. Includes compounds that are derived from carboxylic acids.
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2-Bromoacetamide is a disinfection byproduct known to inactivate liver alcohol dehydrogenase and interfere with microtubule and actin cytoskeletal function. It has also been identified as a potent developmental toxicant in animals.
Inactivates liver alcohol dehydrogenase
Interferes with microtubule and actin cytoskeletal function
Functions as a potent developmental toxicant in animals
Reduces egg cylinder formation rate in mouse embryos (in vitro)
Disrupts cell lineage differentiation in mouse embryos (in vitro)
Reduces first polar body extrusion rate in mouse and human oocytes (in vitro)
Disrupts spindle structure in mouse and human oocytes (in vitro)
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