Isofraxidin, a coumarin component from *Acanthopanax senticosus*, inhibits MMP-7 expression and cell invasion of human hepatoma cells. It inhibits the phosphorylation of ERK1/2 in hepatoma cells and attenuates the expression of iNOS and COX-2. Additionally, Isofraxidin inhibits TLR4/myeloid differentiation protein-2 (MD-2) complex formation.
- Inhibits MMP-7 expression and cell invasion
- Inhibits phosphorylation of ERK1/2
- Attenuates expression of iNOS and COX-2
- Inhibits TLR4/MD-2 complex formation
- Purity: 99.94%
- Appearance: Solid, off-white to yellow color
- Soluble in DMSO: 250 mg/mL