Maralixibat chloride is an orally active ileal bile acid transporter (IBAT) inhibitor. It is used for the research of rare cholestatic liver diseases such as Alagille syndrome (ALGS), progressive familial intrahepatic cholestasis (PFIC), and biliary atresia. Studies have shown Maralixibat chloride to reduce elevated sBA levels, improve liver function, and decrease liver tissue damage in a rat model of cholestasis.
- Orally active ileal bile acid transporter (IBAT) inhibitor
- Used for research of rare cholestatic liver diseases
- Reduces elevated sBA levels
- Improves liver function
- Reduces liver tissue damage in cholestasis models