Azoles
Chem-Impex International, Inc. 4-Imidazoleacetic acid hydrochloride | MFCD00012698 | 25G
4-Imidazoleacetic acid hydrochloride, MFCD00012698, 25G
Medchemexpress LLC Halosulfuron-methyl | 100784-20-1 | 99.8% | 10 MM * 1 ML
Halosulfuron-methyl is a pyrazole sulfonylurea herbicide. It is available for research use only.
Medchemexpress LLC Rad16-I hydrochloride | 2100275-49-6 | 98.9% | 10 MG
RAD16-I hydrochloride is a soft nanofibrous self-assembling peptide. It provides a suitable microenvironment for the proliferation and differentiation of human mesenchymal stem cells (hMSC) into chondrocytes. It is also an ionic complementary peptide that has been used as a model to investigate the potential amyloid-like staining properties of Self-Assembling Peptide Nanofibers (SAPNFs).
- Provides a suitable microenvironment for human mesenchymal stem cells' (hMSC) proliferation and differentiation into chondrocytes.
- Used to check potential amyloid-like staining properties of SAPNFs.
Medchemexpress LLC NS-638 | 150493-34-8 | 99.8% | 325.72 g/mol | C15H11ClF3N3 | 2 MG
NS-638 is a small nonpeptide research compound that acts as a Ca2+-channel blocker. It inhibits K+-stimulated intracellular Ca2+ elevation with an IC50 of 3.4 μM and is supplied as a solid or as DMSO solutions for laboratory use.
- Potent Ca2+ channel blocker with IC50 3.4 μM.
- High supplied purity (reported 99.84%).
- Available as solid and 10 mM DMSO solution formats.
- Molecular weight 325.72 g/mol.
- Powder storage: -20°C (3 years) or 4°C (2 years); in solvent: -80°C (2 years) or -20°C (1 year).
Sigma Aldrich Fine Chemicals Biosciences Candesartan cilexetil United States Pharmacopeia (USP) Reference Standard | 145040-37-5 | MFCD00871371 | 100MG
Candesartan cilexetil United States Pharmacopeia (USP) Reference Standard | Mol Wt: 610.66 | 145040-37-5 | MFCD00871371 | 100MG
![eMolecules IMIDAZO[1,2-B]PYRIDAZINE-6-CARBOXYLIC ACID | 769109-13-9 | MFCD11044772 | 1g](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502171830.JPG-250.jpg)
eMolecules IMIDAZO[1,2-B]PYRIDAZINE-6-CARBOXYLIC ACID | 769109-13-9 | MFCD11044772 | 1g
AstaTech | IMIDAZO[1,2-B]PYRIDAZINE-6-CARBOXYLIC ACID | 1g | 449721334 | 27357 | 95.000 | 769109-13-9 | MFCD11044772 | 163.136 | C7H5N3O2
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Selleck Chemical LLC NG 52
NG-52 is a tri-substituted purine that binds to the ATP-binding site of yeast cyclin-dependent kinases inhibiting Cdc28p and Pho85p with IC50s of 7 and 2 M respectively
Medchemexpress LLC CDDO-dhTFEA | 1191265-33-4 | 99.64% | 574.72 | 50 MG
CDDO-dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound that potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB. It restores hypertension (MAP), increases Nrf2 and the expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis, and inflammation in chronic kidney disease (CKD) rats. For research use only, not for sale to patients.
- Potently activates Nrf2.
- Inhibits the pro-inflammatory transcription factor NF-κB.
- Attenuates activation of NF-κB and transforming growth factor-β pathways.
- Reduces glomerulosclerosis, interstitial fibrosis, and inflammation in chronic kidney disease (CKD) rats.
- Upregulates expression of antioxidant enzymes.
- Protects pancreatic tissue and exhibits anti-inflammatory activity.
![eMolecules Medchem Express / Cenicriviroc Mesylate / 1mg / 446264726 / HY-14882A / / 497223-28-6 / [null] / 793.050 / C42H56N4O7S2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502447917.PNG-250.jpg)
eMolecules Medchem Express / Cenicriviroc Mesylate / 1mg / 446264726 / HY-14882A / / 497223-28-6 / [null] / 793.050 / C42H56N4O7S2
Medchem Express / Cenicriviroc Mesylate / 1mg / 446264726 / HY-14882A / / 497223-28-6 / [null] / 793.050 / C42H56N4O7S2
Medchemexpress LLC Upacicalcet sodium | 2052969-18-1 | 99.9% | 373.75 | 1 ML
Upacicalcet sodium is a non-peptide calcimimetic agent that functions as a calcium-sensing receptor (CaSR) agonist. It is used in secondary hyperparathyroidism (SHPT) research due to its ability to decrease serum intact parathyroid hormone (iPTH) and calcium (Ca2+) levels, which helps reduce hypocalcemia and gastrointestinal complications. This compound also improves vascular calcification and bone disorders in models of adenine-induced SHPT and inhibits cortical pore formation and bone fibrosis in rats with chronic kidney disease (CKD).
- Functions as a CaSR agonist (EC50 = 10.8 nM)
- Increases intracellular Ca2+ and IP-1 in human CaSR-expressing cells
- Reduces serum iPTH, Ca2+, and Pi levels in rats
- Inhibits parathyroid hyperplasia in CKD rat models
- Inhibits ectopic calcification and cortical hole formation in CKD rat models
eMolecules Medchem Express / GSK461364 / 5mg / 446271172 / HY-50877 / / 929095-18-1 / MFCD12755419 / 543.610 / C27H28F3N5O2S
Medchem Express / GSK461364 / 5mg / 446271172 / HY-50877 / / 929095-18-1 / MFCD12755419 / 543.610 / C27H28F3N5O2S