CA/MAO-B-IN-1 is a dual inhibitor targeting human brain carbonic anhydrases (CA) and Monoamine Oxidase-B (MAO-B). It demonstrates high potency with IC50s of 8.8 nM and 7.0 nM, respectively, and shows a predicted human oral absorption of 71.9%. This compound is for research use only.
- Dual inhibitor for human brain carbonic anhydrases and Monoamine Oxidase-B
- Reverts the formation of reactive oxygen species (ROS)
- Exhibits neuro- and mitochondrial protective effects
- Improves cell viability in SH-SY5Y cells damaged by Aβ1-42