Azoles
Apexbio Technology LLC Carbimazole 22232-54-8 1g
Carbimazole (CAS 22232-54-8) is a small-molecule inhibitor targeting thyroid peroxidase (TPO) It is designed to inhibit TPO-mediated iodination and coupling of thyroglobulin tyrosine residues thereby reducing thyroid hormone biosynthesis Carbimazole exerts its biological activity primarily through metabolic conversion to methimazole which suppresses TPO enzymatic function Based on these pharmacological properties Carbimazole holds research potential in studies of hyperthyroidism endocrine modulation experimental neurology and inflammation models
Apexbio Technology LLC Carbimazole 22232-54-8 10mM (in 1mL DMSO)
Carbimazole (CAS 22232-54-8) is a small-molecule inhibitor targeting thyroid peroxidase (TPO) It is designed to inhibit TPO-mediated iodination and coupling of thyroglobulin tyrosine residues thereby reducing thyroid hormone biosynthesis Carbimazole exerts its biological activity primarily through metabolic conversion to methimazole which suppresses TPO enzymatic function Based on these pharmacological properties Carbimazole holds research potential in studies of hyperthyroidism endocrine modulation experimental neurology and inflammation models
Apexbio Technology LLC Carbimazole 22232-54-8 5g
Carbimazole (CAS 22232-54-8) is a small-molecule inhibitor targeting thyroid peroxidase (TPO) It is designed to inhibit TPO-mediated iodination and coupling of thyroglobulin tyrosine residues thereby reducing thyroid hormone biosynthesis Carbimazole exerts its biological activity primarily through metabolic conversion to methimazole which suppresses TPO enzymatic function Based on these pharmacological properties Carbimazole holds research potential in studies of hyperthyroidism endocrine modulation experimental neurology and inflammation models
Medchemexpress LLC Carbimazole | 22232-54-8 | 98.0% | 1 G
Carbimazole is an orally active antithyroid agent that rapidly converts to Methimazole after absorption. It prevents the thyroid peroxidase enzyme from iodinating and coupling tyrosine residues on thyroglobulin, thereby reducing the production of thyroxine. Carbimazole also exhibits anti-inflammatory and neuronal-protective activities, suggesting its use for hyperthyroidism and neurological research.
- Orally active antithyroid agent
- Converts to methimazole after absorption
- Reduces thyroxine production
- Exhibits anti-inflammatory activities
- Exhibits neuronal-protective activities
Medchemexpress LLC Carbimazole | 22232-54-8 | 98.0% | 1 ML
Carbimazole is an orally active antithyroid agent that converts to Methimazole after absorption. It reduces the production of thyroxine by preventing the thyroid peroxidase enzyme from iodinating and coupling tyrosine residues on thyroglobulin. This agent also exhibits anti-inflammatory and neuronal-protective activities.
- Orally active antithyroid agent.
- Converts to Methimazole in the body.
- Reduces thyroxine production.
- Displays anti-inflammatory activity.
- Shows neuronal-protective activity.
- Suggested for application in hyperthyroidism and neurological research.