2,3-Dihydroxy-4-methoxyacetophenone, derived from *Cynanchum paniculatum*, is a neuroprotective compound with potential for Alzheimer's disease research. It improves cognitive function and protects HT22 cells from glutamate-induced cell death by inhibiting Ca2+ accumulation and exhibiting antioxidative activity. *In vivo*, it has shown to improve scopolamine-induced spatial memory impairment.
- Derived from *Cynanchum paniculatum*
- Exhibits neuroprotective activity
- Protects HT22 cells from glutamate-induced cell death
- Inhibits Ca2+ accumulation
- Demonstrates antioxidative activity
- Improves scopolamine-induced spatial memory impairment *in vivo*