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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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m-PEG3-aldehyde (stabilized with BHT) is a methoxy-terminated PEG3 aldehyde used as a PROTAC linker and synthetic building block for bioconjugation. The product is stabilized with butylated hydroxytoluene (BHT) and is supplied as a solid in milligram quantities for research use only. Molecular formula C8H16O4, molecular weight 176.21 g/mol.
Aldehyde functional group for facile conjugation.
Methoxy-terminated PEG3 spacer provides flexibility and solubility.
Stabilized with BHT to preserve aldehyde integrity during storage.
High reported purity of 98.0% suitable for synthetic applications.
Available in multiple small package sizes for laboratory-scale work.
Intended for research use only; not for clinical or human use.
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Aldehyde-benzyl-PEG5-alkyne is a PEG-based PROTAC linker used in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Alkyne group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with molecules possessing Azide groups. PROTACs themselves consist of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase, and the other targets a specific protein, leveraging the intracellular ubiquitin-proteasome system for selective protein degradation. This product is intended for research use only.
PEG-based PROTAC linker
Click chemistry reagent
Contains an alkyne group for CuAAc reactions
Utilizes the ubiquitin-proteasome system for selective protein degradation
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
A biotinylated reagent used for the detection and quantification of apurinic/apyrimidinic (AP) sites in damaged DNA; reacts with aldehyde groups formed when reactive oxygen species depurinate DNA, thereby covalently linking biotin to these AP sites.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More