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Organic compounds that contain one or more carbonyl (a carbon atom with a double bond to an oxygen atom) functional groups. Includes compounds with functional groups that contain a carbonyl in their structure such as ketones, aldehydes, and others.
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HO-3867 an analog of curcumin is a selective STAT3 inhibitor that inhibits its phosphorylation transcription and DNA binding without affecting the expression of other active STATs HO-3867 induces apoptosis
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Menadione(Vitamin K3) bisulfite sodium a fat-soluble compound is an inhibitor of Cdc25 phosphatase and mitochondrial DNA polymerase (pol ) used as a nutritional supplement
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β-D-Glucopyranosyl abscisate (ABA-GE) is a hydrolyzable abscisic acid (ABA) conjugate that accumulates in the vacuole and presumably also in the endoplasmic reticulum. The deconjugation of β-D-Glucopyranosyl abscisate allows the rapid formation of free ABA in response to abiotic stress conditions such as dehydration and salt stress. β-D-Glucopyranosyl abscisate contributes to the maintenance of ABA homeostasis. For research use only.
Accumulates in the vacuole and endoplasmic reticulum.
Allows rapid formation of free ABA in response to abiotic stress conditions like dehydration and salt stress.
Contributes to the maintenance of ABA homeostasis.
Vacuolar transport is mediated by ATP-binding cassette and proton-antiport mechanisms.
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trans-trans-Muconic acid is a urinary metabolite of benzene, frequently utilized as a biomarker for human exposure to benzene. It is also known to be mutagenic in E. coli assays.
Analytical standard for research and analytical applications.
Used as a biomarker of exposure to benzene in humans.
Mutagenic in E. coli assay.
Human endogenous metabolite.
Microbial metabolite.
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trans-trans-Muconic acid-d4 is the deuterium labeled trans-trans-Muconic acid. It is a urinary metabolite of benzene and has been used as a biomarker of exposure to benzene in humans. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Can be used as a tracer.
Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
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2'-Deoxy-2'-fluoroarabino inosine is a purine nucleoside analog. These analogs exhibit broad antitumor activity, specifically targeting indolent lymphoid malignancies. The anticancer mechanisms associated with these compounds involve the inhibition of DNA synthesis and the induction of apoptosis.
Purine nucleoside analog
Exhibits broad antitumor activity
Targets indolent lymphoid malignancies
Inhibits DNA synthesis
Induces apoptosis
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2′-Deoxy-GDP (dGDP) trisodium is an analog of guanosine monophosphate (GMP) that acts as an inhibitor of hypoxanthine phosphoribosyltransferase (HGPRT). This enzyme is crucial for the purine recycling pathway in all protozoan parasites. It has an IC50 of 12.5 μM.