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2,3-Dihydroxy-4-methoxyacetophenone is a neuroprotective compound isolated from *Cynanchum paniculatum*. It protects HT22 cells from glutamate-induced cell death, inhibits [Ca2+] accumulation, and exhibits antioxidative activity. This compound improves cognitive function and shows potential for research in Alzheimer's disease.
Neuroprotective compound derived from *Cynanchum paniculatum*.
Improves cognitive function.
Protects HT22 cells from glutamate-induced cell death.
Inhibits [Ca2+] accumulation in HT22 cells.
Exhibits antioxidative activity.
Improves impairment of spatial memory induced by scopolamine.
Appears as a white to yellow solid.
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Chemical. CAS 63775-96-2. Formula C63H113N11O12. MW 1216.7. Isolated from Fusarium solani. Potent inhibitor of tumor promoting phorbol ester TPA/PMA AG-CN2-0010 effects in vivo. Antifungal. Moderate immunosuppressant. Calcineurin inhibitor with lower activity than Cyclosporin A AG-CN2-0079. Moderate inhibitor of formyl peptide-induced superoxide formation.
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trans-Zeatin is a plant cytokinin that plays a vital role in cell growth, differentiation, and division. It also acts as an inhibitor of UV-induced MEK/ERK activation.
Plant cytokinin
Inhibits UV-induced MEK/ERK activation
Plays a role in cell growth, differentiation, and division
Available in solid and solution forms
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4-Thio-2'-deoxyuridine is a purine nucleoside analog used in biochemical and cellular research to probe nucleic acid chemistry and antitumor mechanisms. It can inhibit DNA synthesis and promote apoptosis in experimental systems. Supplied as a light yellow solid with high reported purity, the compound is available in small milligram packages and as ready-to-use DMSO solutions for assay development and screening.
Purine nucleoside analog for research applications.
Molecular formula C9H12N2O4S; MW 244.27 g·mol⁻¹.
CAS number 5580-20-1 for unambiguous identification.
High purity (reported 99.78%).
Solid form; light yellow to yellow appearance.
Storage recommendations provided for powder and solvent solutions.
Available in small packaging sizes, including 25 mg.
Concentration options supplied for solution-based assays (e.g., DMSO stocks).
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