Aminobenzoic acids and derivatives
Chemscene 4-Bromo-3-fluorophenol | 25g | CS-W008805 | 98% | 121219-03-2 | MFCD00051907 | 191 00 | C6H4BrFO
Chemscene | 4-Bromo-3-fluorophenol | 25g | CS-W008805 | 98% | 121219-03-2 | MFCD00051907 | 191 00 | C6H4BrFO
Medchemexpress LLC α-Hydroxyglutaric acid disodium | 40951-21-1 | 98.0% | 192.08 | 25 MG
α-Hydroxyglutaric acid disodium is an α-hydroxy acid form of glutaric acid. It is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methylcytosine (5mC) hydroxylases. Research indicates that isocitrate dehydrogenase 1 (IDH1) and IDH2 mutations, common in gliomas and acute myeloid leukemia, lead to altered production of α-ketoglutarate and α-Hydroxyglutaric acid disodium. Furthermore, it has been shown to inhibit the activity of TET 5-methylcytosine hydroxylases and, in U-87MG cells, increases HIF-1α while decreasing endostatin.
- Endogenous metabolite
- Competitive inhibitor of α-ketoglutarate-dependent dioxygenases
- Inhibits histone demethylases
- Inhibits TET family of 5-methylcytosine (5mC) hydroxylases
- Increases HIF-1α and decreases endostatin in U-87MG cells
eMolecules 1255666-48-8 | tert-Butyl 4-amino-3,3-difluoropiperidine-1-carboxylate | Ambeed | MFCD16250242 | 236.263 | C10H18F2N2O2 | 95.000 | CC(C)(C)OC(=O)N1CCC(N)C(F)(F)C1 | 5g | 525080025
tert-Butyl 4-amino-3,3-difluoropiperidine-1-carboxylate | Ambeed | 1255666-48-8 | MFCD16250242 | 236.263 | C10H18F2N2O2 | 95.000 | CC(C)(C)OC(=O)N1CCC(N)C(F)(F)C1 | 5g | 525080025
Chemscene 4-Bromo-4 -iodo-1 1 -biphenyl | 100g | CS-W009791 | 98% | 105946-82-5 | MFCD17676204 | 359 00 | C12H8BrI
Chemscene | 4-Bromo-4 -iodo-1 1 -biphenyl | 100g | CS-W009791 | 98% | 105946-82-5 | MFCD17676204 | 359 00 | C12H8BrI
Medchemexpress LLC AC-264613 | 1051487-82-1 | 98.3% | C19H18BrN3O2 | 1 MG
AC-264613 | 1051487-82-1 | 98.3% | C19H18BrN3O2 | 1 MG
Accela Chembio Inc 2-amino-5-chloro-3-methylbenzoic Acid | 100g | 20776-67-4 | MFCD02358895 | 97+% | Shelf Life: 1440 Days | Light Sensitive
2-amino-5-chloro-3-methylbenzoic Acid | 100g | 20776-67-4 | MFCD02358895 | 97+% | Shelf Life: 1440 Days | Light Sensitive
Aobchem 3-(1 1-Difluoroethyl)benzoic acid | ≥97% | CAS 55805-17-9 | C9H8F2O2 | 1g
3-(1 1-Difluoroethyl)benzoic acid | ≥97% | CAS 55805-17-9 | C9H8F2O2 | 1g
Aobchem 4-(3 4-Difluorophenoxy)benzoic acid | ≥97% | CAS 1153088-42-6 | C13H8F2O3 | 5g
4-(3 4-Difluorophenoxy)benzoic acid | ≥97% | CAS 1153088-42-6 | C13H8F2O3 | 5g
Aobchem 4-Bromo-2-chloro-3-methylbenzonitrile | ≥97% | CAS 1254034-53-1 | C8H5BrClN | 1g
4-Bromo-2-chloro-3-methylbenzonitrile | ≥97% | CAS 1254034-53-1 | C8H5BrClN | 1g
Chemscene 2 3-Dihydro-7-azaindole | 100g | CS-B0149 | 98% | 10592-27-5 | MFCD06659751 | 120 16 | C7H8N2
Chemscene | 2 3-Dihydro-7-azaindole | 100g | CS-B0149 | 98% | 10592-27-5 | MFCD06659751 | 120 16 | C7H8N2