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Organic compounds that consist of a phenyl group attached to an amino group; aniline is the simplest aromatic amine. Anilines with additional substitutions are included.
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3,4-Dibromo-Mal-PEG2-amine TFA is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs are compounds comprising two distinct ligands linked together; one ligand targets an E3 ubiquitin ligase, while the other targets the protein of interest. This design enables PROTACs to leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
PEG-based PROTAC linker
Utilized in the synthesis of PROTACs
Enables selective degradation of target proteins
Targets E3 ubiquitin ligase and protein of interest
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