Benzenesulfonamides
Medchemexpress LLC HY-18054 5mg Medchemexpress, BVT 2733 CAS:376640-41-4 Purity:>98%
Medchemexpress, HY-18054 5mg BVT 2733 CAS:376640-41-4 BVT 2733 is a potent, selective, and orally active non-steroidal 11β-hydroxydehydrogenase 1 (11β-HSD1) inhibitor. BVT 2733 is potently against the mouse enzyme (IC50=96 nM) over the human enzyme (IC50=3341 nM). BVT 2733 has the potential for the study of arthritis and obesity related disease. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-18741 5mg Medchemexpress, VR23 CAS:1624602-30-7 Purity:>98%
Medchemexpress, HY-18741 5mg VR23 CAS:1624602-30-7 VR23 is a small molecule that potently inhibits the activities of trypsin-like proteasomes (IC50=1 nM), chymotrypsin-like proteasomes (IC50=50-100 nM), and caspase-like proteasomes (IC50=3 μM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-18253 5mg Medchemexpress, Udenafil CAS:268203-93-6 Purity:>98%
Medchemexpress, HY-18253 5mg Udenafil CAS:268203-93-6 Udenafil (DA8159) is a potent, selective and orally active phosphodiesterase type 5 (PDE5) inhibitor. Udenafil also inhibits cGMP hydrolysis and can be used for erectile dysfunction research. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Sigma Aldrich Fine Chemicals Biosciences Ribonucleic acid from torula yeast Type VI | 63231-63-0 | MFCD00132195 | 25g
Ribonucleic acid from torula yeast Type VI | 63231-63-0 | MFCD00132195 | 25g
Electron Microscopy Sciences SEM Scintillator YAP 19.0x1 mm
YAP (Yttrium Aluminum Perovskite activated by Ce3+) shares the same advantages as YAG but is more efficient in terms of light output than YAG crystals. As well, the emission spectrum peaks at about 378nm, and this corresponds closely to the maximum sensitivity of the S11 photocathode which in general is used in most scanning electron microscopes. (There would be more improvement in signal by using a YAP crystal rather than YAG in these microscopes). The decay time of YAP (40ns) is faster than YAG (80ns) so its overall performance is superior to YAG.
YAP crystals should be coated with 50nm of aluminum prior to use. Note: P-47 is usually in-stock. YAG and YAP delivery time is 6-8 weeks. Use with JEOL U3, JSM2 scanning electron microscopes.
Medchemexpress LLC HY-19995 5mg Medchemexpress, GSK137647A CAS:349085-82-1 Purity:>98%
Medchemexpress, HY-19995 5mg GSK137647A CAS:349085-82-1 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-19977 5mg Medchemexpress, YU238259 CAS:1943733-16-1 Purity:>98%
Medchemexpress, HY-19977 5mg YU238259 CAS:1943733-16-1 YU238259 is an inhibitor of homology-dependent DNA repair (HDR), used for cancer research. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-15357 5mg Medchemexpress, ALK inhibitor 1 CAS:761436-81-1 Purity:>98%
Medchemexpress, HY-15357 5mg ALK inhibitor 1 CAS:761436-81-1 ALK inhibitor 1 (compound 17) is a potent pyrimidin ALK inhibitor. ALK inhibitor 1 is a potent inhibitor of testis-specific serine/threonine kinase 2 (TSSK2; IC50=31 nM) and focal adhesion kinase (FAK; IC50=2 nM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC HY-B0397 10mg Medchemexpress, Dichlorphenamide CAS:120-97-8 Purity:>98%
Medchemexpress, HY-B0397 10mg Dichlorphenamide CAS:120-97-8 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Apexbio Technology LLC Sildenafil Citrate 171599-83-0 500mg
Sildenafil Citrate is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) PDE5 mediates degradation of cGMP a signaling molecule regulating smooth muscle tone vascular dilation and blood flow By inhibiting PDE5 Sildenafil Citrate elevates intracellular cGMP levels It has an IC50 value of approximately 3 6 nM against PDE5 Pharmacologically Sildenafil Citrate induces relaxation of smooth muscle tissues including penile corpus cavernosum and vascular smooth muscle thus facilitating increased blood flow It is widely utilized in biomedical research involving erectile dysfunction therapies and the management of pulmonary arterial hypertension (PAH)
Medchemexpress LLC 1(2H)-Phthalazinone, 4-(1,3-dioxan-2-ylmethyl)-2-[[4-(4-methylphenyl)-2-thiazolyl]methyl]- | 1614225-93-2 | 99.3% | 50 MG
PHT-7.3 is a selective inhibitor of connector enhancer of kinase suppressor of Ras 1 (Cnk1) pleckstrin homology (PH) domain (Kd=4.7 μM). It inhibits mutant KRas, but not wild-type KRas cancer cell and tumor growth and signaling, and exhibits antitumor activity. In vivo studies show that PHT-7.3 demonstrates cytostatic antitumor activity in mut-KRas(G12S) A549 xenograft and mut-KRasG12V H441 xenograft models.
- Selective inhibitor of Cnk1 PH-domain (Kd=4.7 μM).
- Inhibits mutant-KRas cancer cell and tumor growth and signaling.
- Exhibits antitumor activity.
- Demonstrates cytostatic antitumor activity in mut-KRas(G12S) A549 xenograft and mut-KRasG12V H441 xenograft models.
Medchemexpress LLC HY-15724 5mg Medchemexpress, Vercirnon CAS:698394-73-9 Purity:>98%
Medchemexpress, HY-15724 5mg Vercirnon CAS:698394-73-9 Vercirnon (GSK1605786A) is an orally bioavailable, selective, and potent antagonist of CCR9. Vercirnon inhibits CCR9-mediated Ca2+ mobilization and chemotaxis on Molt-4 cells with IC50 values of 5.4 and 3.4 nM, respectively. Vercirnon is selective for CCR9 over CCR1-12 and CX3CR1-7 (IC50s>10 µM for all). Vercirnon is an equipotent inhibitor of CCL25-directed chemotaxis of both splice forms of CCR9 (CCR9A and CCR9B) with IC50 values of 2.8 and 2.6 nM, respectively. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Electron Microscopy Sciences SEM Scintillator YAP 20.0x2 mm
YAP (Yttrium Aluminum Perovskite activated by Ce3+) shares the same advantages as YAG but is more efficient in terms of light output than YAG crystals. As well, the emission spectrum peaks at about 378nm, and this corresponds closely to the maximum sensitivity of the S11 photocathode which in general is used in most scanning electron microscopes. (There would be more improvement in signal by using a YAP crystal rather than YAG in these microscopes). The decay time of YAP (40ns) is faster than YAG (80ns) so its overall performance is superior to YAG.
YAP crystals should be coated with 50nm of aluminum prior to use. Note: P-47 is usually in-stock. YAG and YAP delivery time is 6-8 weeks. Use with Philips scanning electron microscopes.