Benzenesulfonamides
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Selleck Chemical LLC CDKI-73
CDKI-73 (LS-007) is a potent CDK inhibitor in vitro with IC50 of 8 17 nM 3 27 nM 8 18 nM and 5 78 nM for CDK1 CDK2 CDK4 and CDK9 respectively CDKI-73 induces apoptosis in cancer cells CDKI-73 is an orally bioavailable and highly efficacious CDK9 inhibitor against acute myeloid leukemia
