Benzenesulfonic acids and derivatives
Medchemexpress LLC p-Toluenesulfonic acid monohydrate | 6192-52-5 | MFCD00142137 | 99.8% | 190.22 g·mol⁻¹ | C7H10O4S | 500 G
p-Toluenesulfonic acid monohydrate is a strong organic sulfonic acid supplied as the monohydrate salt. It is commonly used as an acid catalyst in organic synthesis and for research and analytical applications. The solid material offers high purity and is suitable for laboratory reactions, analytical standards, and catalytic transformations.
- Strong organic acid and catalyst for dehydration and esterification reactions.
- Supplied as a monohydrate solid for convenient handling and storage.
- High purity (≈99.8%) appropriate for research and analytical use.
- Suitable for use as an analytical standard and reagent in synthesis.
- Compatible with common polar organic solvents; readily soluble.
- Available in multiple pack sizes to support small- and large-scale work.
eMolecules Chem-Impex Methyl p-toluenesulfonate 5kg 703110501 36908 0 000 80-48-8 MFCD00008417 186 230 C8H10O3S
Chem-Impex Methyl p-toluenesulfonate 5kg 703110501 36908 0 000 80-48-8 MFCD00008417 186 230 C8H10O3S
Medchemexpress LLC p-toluenesulfonic acid monohydrate | 6192-52-5 | MFCD00142137 | 99.8% | 190.22 g/mol | C7H10O4S | 1 ML
p-Toluenesulfonic acid monohydrate (CAS 6192-52-5) is a strong organic acid used as an acid catalyst in organic synthesis and laboratory research. It is available as a solid monohydrate and as a ready-to-use 10 mM solution in DMSO for convenient handling and dosing.
- Strong organic acid suitable for acid-catalyzed reactions.
- Ready-to-use 10 mM solution in DMSO for convenient dosing and reduced preparation time.
- High purity suitable for analytical and synthetic applications.
- Monohydrate form with defined molecular weight and chemical formula for reproducibility.
- Applicable to esterification, dehydration, and other acid-catalyzed transformations.
Medchemexpress LLC Propionylcholine p-toluenesulfonate | 1866-13-3 | MFCD00059975 | 99.6% | 331.43 g/mol | C15H25NO5S | 250 MG
Propionylcholine p-toluenesulfonate is a quaternary ammonium choline ester supplied as the p-toluenesulfonate salt for use in biochemical and neuroscience research. It is used to probe cholinergic signaling and esterase activity, and is provided with manufacturer analytical documentation for laboratory applications.
- Quaternary choline ester for cholinergic studies.
- Supplied as the p-toluenesulfonate salt for handling stability.
- High purity suitable for analytical and research assays.
- Available in small laboratory pack sizes for convenience.
- Documentation includes COA and SDS for traceability.
Medchemexpress LLC P-toluenesulfonic acid-d7 monohydrate | 1219795-22-8 | 99.8% | 197.26 | C7H3D7O4S | 10 MG
p-Toluenesulfonic acid-d7 monohydrate is a deuterium-labeled analog of p-toluenesulfonic acid (monohydrate) used as a strong organic acid and catalyst in organic synthesis and analytical studies. The deuterium labeling supports mechanistic investigations and NMR tracing, and the material is supplied at high isotopic and chemical purity for research use.
- Deuterium-labeled for tracing and NMR studies.
- Monohydrate form for consistent handling and reproducibility.
- High purity (99.76%) suitable for analytical and research applications.
- Functions as a strong organic acid and catalyst in synthesis.
- Available in small pack sizes for laboratory and analytical work.
Medchemexpress LLC I-138 | 2098211-50-6 | C26H23F3N6O | 1 ML
I-138 is an orally active, reversible inhibitor of USP1-UAF1, with an IC50 of 4.1 nM and Ki of 5.4 nM. It induces monoubiquitination of FANCD2 and PCNA in cells and eliminates USP1 autocleavage in cells. It is intended for research use only.
- Eliminates USP1 self-lysis in HAP-1 USP1 WT and knockout cells
- Induces monoubiquitination of FANCD2 and PCNA in MDA-MB-436 cells
- Dose-dependently inhibits MDA-MB-436 cell viability
- Results in USP1 inhibition and modest antitumor activity in mice bearing MDA-MB-436 tumors
- Benefits BRCA1/2 mutant tumor inhibition in vivo when combined with Niraparib
Medchemexpress LLC I-138 | 2098211-50-6 | C26H23F3N6O | 25 MG
I-138 is an orally active, reversible inhibitor of USP1-UAF1, with an IC50 of 4.1 nM and a Ki of 5.4 nM. It induces monoubiquitination of FANCD2 and PCNA in cells and eliminates USP1 autocleavage in cells. It is structurally related to ML323.
- Reversible inhibitor of USP1-UAF1
- Induces monoubiquitination of FANCD2 and PCNA in cells
- Eliminates USP1 autocleavage in cells
- Inhibits MDA-MB-436 cell viability
- Shows modest antitumor activity in mice bearing MDA-MB-436 tumors
- Can be combined with Niraparib for BRCA1/2 mutant tumor inhibition
Medchemexpress LLC I-138 | 2098211-50-6 | C26H23F3N6O | 1 MG
I-138 is an orally active, reversible inhibitor of USP1-UAF1 (IC50: 4.1 nM; Ki: 5.4 nM), structurally related to ML323 (HY-17543). I-138 induces monoubiquitination of FANCD2 and PCNA in cells and eliminates USP1 autocleavage in cells.
- Orally active and reversible inhibitor of USP1-UAF1.
- Potent inhibitory activity against USP1-UAF1 (IC50: 4.1 nM; Ki: 5.4 nM).
- Induces monoubiquitination of FANCD2 and PCNA in cells.
- Eliminates USP1 autocleavage in cells.
- Demonstrates modest antitumor activity in mice bearing MDA-MB-436 tumors.
- Shows enhanced inhibition of BRCA1/2 mutant tumors in vivo when combined with the PARP inhibitor Niraparib.
Medchemexpress LLC I-138 | 2098211-50-6 | C26H23F3N6O | 50 MG
I-138 is an orally active, reversible inhibitor of USP1-UAF1 (IC50: 4.1 nM; Ki: 5.4 nM), structurally related to ML323. It induces monoubiquitination of FANCD2 and PCNA in cells and eliminates USP1 autocleavage in cells.
- Eliminates USP1 self-lysis in HAP-1 USP1 WT and knockout cells
- Induces monoubiquitination of FANCD2 and PCNA in MDA-MB-436 cells
- Dose-dependently inhibits MDA-MB-436 cell viability
- Results in USP1 inhibition and modest antitumor activity in mice bearing MDA-MB-436 tumors
- Benefits BRCA1/2 mutant tumor inhibition when combined with Niraparib
Medchemexpress LLC Setmelanotide (monoacetate) | 2759937-80-7 | 99.8% | 1177.36 | 25 MG
Setmelanotide (monoacetate) is a melanocortin 4 receptor (MC4R) agonist. It acts on human and rat MC4R with EC50 values of 0.27 nM and 0.28 nM, respectively, and is intended for research use only.
- Acts on human and rat MC4R
- Stable as a solid
- Suitable for research use
eMolecules DL-Phosphinothricin, monoammonium salt | 77182-82-2 | | 1g
Apollo Scientific | DL-Phosphinothricin, monoammonium salt | 1g | 562428419 | BIP0679 | | 77182-82-2 | | 198.159 | C5H15N2O4P
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eMolecules 3-Sulfobenzoic acid monosodium salt | 17625-03-5 | MFCD00066378 | 25g
Combi-Blocks, Inc. | 3-Sulfobenzoic acid monosodium salt | 25g | 603138216 | QF-2754 | 95.000 | 17625-03-5 | MFCD00066378 | 224.160 | C7H5NaO5S
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Medchemexpress LLC Setmelanotide monoacetate | 2759937-80-7 | 99.9% | 1177.36 | 5 MG
Setmelanotide (monoacetate) is a melanocortin 4 receptor (MC4R) agonist that acts on human and rat MC4R with EC50 values of 0.27 nM and 0.28 nM, respectively. It is for research use only and not sold to patients.
- Melanocortin 4 receptor (MC4R) agonist
- Acts on human and rat MC4R
- EC50 values of 0.27 nM (human) and 0.28 nM (rat)
- Available for bulk orders
- Supported by 8 publications in Google Scholar
Medchemexpress LLC 2-Ketoglutaric acid-13C5 | 161096-83-9 | 99.1% | 151.06 | 1 MG
2-Ketoglutaric acid-13C5 is a 13C labeled version of 2-Ketoglutaric acid, an intermediate in the Krebs cycle. It is also involved in nitrogen-assimilatory reactions and acts as a reversible inhibitor of tyrosinase.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC 2-Ketoglutaric acid-d6 | 1173021-86-7 | 98.6% | 152.14 | 10 MG
2-Ketoglutaric acid-d6 is the deuterium labeled variant of 2-Ketoglutaric acid. It is an intermediate in the Krebs cycle for ATP or GTP production and serves as the primary carbon skeleton for nitrogen-assimilatory reactions. This compound also acts as a reversible inhibitor of tyrosinase (IC50=15 mM).
- Used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated for potential impact on pharmacokinetic and metabolic profiles of drugs.