Benzophenones

Nepafenac 98.0+%, TCI America™

CAS: 78281-72-8 Molecular Formula: C15H14N2O2 Molecular Weight (g/mol): 254.29 MDL Number: MFCD08067732 InChI Key: QEFAQIPZVLVERP-UHFFFAOYSA-N Synonym: 2-Amino-3-benzoylbenzeneacetamide, 2-(2-Amino-3-benzoylphenyl)acetamide PubChem CID: 151075 ChEBI: CHEBI:75922 IUPAC Name: 2-(2-amino-3-benzoylphenyl)acetamide SMILES: NC(=O)CC1=CC=CC(C(=O)C2=CC=CC=C2)=C1N

Apexbio Technology LLC Nepafenac 78281-72-8 25mg

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Nepafenac (CAS 78281-72-8) is a small-molecule inhibitor targeting cyclooxygenase enzymes COX-1 and COX-2 It is designed to inhibit these enzymes thereby reducing prostaglandin E2 (PGE2) biosynthesis and modulating ocular inflammatory pathways Nepafenac exerts its biological activity primarily through COX-1 and COX-2 inhibition In cell-based studies nepafenac demonstrates inhibitory activity with IC50 values of approximately 250 nM for COX-1 and 150 nM for COX-2 In LPS-induced inflammation models topical application reduces retinal PGE2 concentrations Additionally it has been studied as an inhibitor of cellular proliferation in human uveal melanoma cell lines (SP6 5 92 1 OCM-1 MKT-BR UW-1) Based on these pharmacological properties nepafenac holds research potential in ophthalmologic studies involving inflammatory pathways and ocular malignancies

Sigma Aldrich Fine Chemicals Biosciences Nepafenac >=98% (HPLC) | 78281-72-8 | MFCD08067732 | 50MG

Nepafenac >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 254.28 | 78281-72-8 | MFCD08067732 | 50MG

eMolecules​ Ambeed / 2-(2-Amino-3-benzoylphenyl)acetamide / 1mg / 722703807 / A174101 / / 78281-72-8 / MFCD08067732 / 254.289 / C15H14N2O2

Ambeed / 2-(2-Amino-3-benzoylphenyl)acetamide / 1mg / 722703807 / A174101 / / 78281-72-8 / MFCD08067732 / 254.289 / C15H14N2O2