Biphenyls and derivatives
Medchemexpress LLC BIP-135 | 941575-71-9 | 99.9% | 421.24 | 10 MG
BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor, with IC50s of 16 nM and 21 nM for GSK-3α and GSK-3β, respectively. It exhibits neuroprotective effects.
- Potent and selective ATP-competitive GSK-3 inhibitor.
- Exhibits neuroprotective effect.
- Increases survival motor neuron (SMN) protein levels in human SMA fibroblasts (at 25 μM).
- Superior neuroprotective agent in models of oxidative stress (at 20 μM).
- Prolongs median survival time in a Δ7 SMA KO mouse model of spinal muscular atrophy (at 75 mg/kg; i.p.; daily).
Chemscene ChemScene | 4-Cyano-4'-hydroxybiphenyl | 100G | CS-W002275 | 0.98 | 19812-93-2| MFCD00059625 | 195.22
ChemScene | 4-Cyano-4'-hydroxybiphenyl | 100G | CS-W002275 | 0.98 | 19812-93-2| MFCD00059625 | 195.22
Aobchem 3-Bromo-4-chloro-1 1 -biphenyl | 95% | CAS 1537919-83-7 | C12H8BrCl | 1g
3-Bromo-4-chloro-1 1 -biphenyl | 95% | CAS 1537919-83-7 | C12H8BrCl | 1g
Aobchem 2 3-Difluoro-4-(hexyloxy)benzoic acid | ≥97% | CAS 2082696-88-4 | C13H16F2O3 | 1g
2 3-Difluoro-4-(hexyloxy)benzoic acid | ≥97% | CAS 2082696-88-4 | C13H16F2O3 | 1g
Aobchem 1-Fluoro-4-(hexyloxy)-2-methylbenzene | ≥95% | CAS 1513811-81-8 | C13H19FO | 10g
1-Fluoro-4-(hexyloxy)-2-methylbenzene | ≥95% | CAS 1513811-81-8 | C13H19FO | 10g
Aobchem 1-Fluoro-4-(hexyloxy)-2-methylbenzene | ≥95% | CAS 1513811-81-8 | C13H19FO | 5g
1-Fluoro-4-(hexyloxy)-2-methylbenzene | ≥95% | CAS 1513811-81-8 | C13H19FO | 5g
Aobchem 4-Bromo-2-chloro-1 1 -biphenyl | 97% | CAS 58775-86-3 | C12H8BrCl | 5g
4-Bromo-2-chloro-1 1 -biphenyl | 97% | CAS 58775-86-3 | C12H8BrCl | 5g
Aobchem 2-Bromo-4-fluoro-1 1 -biphenyl | ≥97% | CAS 53591-98-3 | C12H8BrF | 5g
2-Bromo-4-fluoro-1 1 -biphenyl | ≥97% | CAS 53591-98-3 | C12H8BrF | 5g
Aobchem 2-Methyl-5-bromobiphenyl | ≥95% | CAS 571903-41-8 | C13H11Br | 250mg
2-Methyl-5-bromobiphenyl | ≥95% | CAS 571903-41-8 | C13H11Br | 250mg
Aobchem 3 -Bromobiphenyl-3-ylboronic acid | ≥95% | CAS 1048990-21-1 | C12H10BBrO2 | 5g
3 -Bromobiphenyl-3-ylboronic acid | ≥95% | CAS 1048990-21-1 | C12H10BBrO2 | 5g
Aobchem 2-Methyl-5-bromobiphenyl | ≥95% | CAS 571903-41-8 | C13H11Br | 5g
2-Methyl-5-bromobiphenyl | ≥95% | CAS 571903-41-8 | C13H11Br | 5g
Aobchem 3-Fluoro-4-biphenylboronic acid | 97% | CAS 409108-13-0 | C12H10BFO2 | 250mg
3-Fluoro-4-biphenylboronic acid | 97% | CAS 409108-13-0 | C12H10BFO2 | 250mg
Aobchem 4-Bromo-2-chloro-1 1 -biphenyl | 97% | CAS 58775-86-3 | C12H8BrCl | 250mg
4-Bromo-2-chloro-1 1 -biphenyl | 97% | CAS 58775-86-3 | C12H8BrCl | 250mg
Aobchem 4-Amino-3-fluorobiphenyl | ≥97% | CAS 76302-56-2 | C12H10FN | 1g
4-Amino-3-fluorobiphenyl | ≥97% | CAS 76302-56-2 | C12H10FN | 1g
Aobchem 2-Fluoro-4-iodo-1 1 -biphenyl | 97% | CAS 56985-88-7 | C12H8FI | 1g
2-Fluoro-4-iodo-1 1 -biphenyl | 97% | CAS 56985-88-7 | C12H8FI | 1g