Biphenyls and derivatives
Medchemexpress LLC BIP-135 | 941575-71-9 | 99.9% | 421.24 | 100 MG
BIP-135 | 941575-71-9 | 99.9% | 421.24 | 100 MG
Medchemexpress LLC BIP-135 | 941575-71-9 | 99.86% | 421.24 | 50 MG
BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor, with IC50s of 16 nM and 21 nM for GSK-3α and GSK-3β, respectively. It exhibits a neuroprotective effect.
- Potent and selective ATP-competitive GSK-3 inhibitor
- IC50 for GSK-3α: 16 nM
- IC50 for GSK-3β: 21 nM
- Increases survival motor neuron (SMN) protein levels in human SMA fibroblasts
- Neuroprotective agent in models of oxidative stress
- Well-tolerated in animal studies; non-toxic
- Prolongs median survival time in SMA mouse models
Aobchem 3-(Hexyloxy)benzoic acid | ≥95% | CAS 200570-98-5 | C13H18O3 | 1g
3-(Hexyloxy)benzoic acid | ≥95% | CAS 200570-98-5 | C13H18O3 | 1g
Aobchem 3-(Hexyloxy)benzoic acid | ≥95% | CAS 200570-98-5 | C13H18O3 | 500mg
3-(Hexyloxy)benzoic acid | ≥95% | CAS 200570-98-5 | C13H18O3 | 500mg
Aobchem 3-Fluoro-4-biphenylboronic acid | 97% | CAS 409108-13-0 | C12H10BFO2 | 250mg
3-Fluoro-4-biphenylboronic acid | 97% | CAS 409108-13-0 | C12H10BFO2 | 250mg
Aobchem 2-Methyl-5-bromobiphenyl | ≥95% | CAS 571903-41-8 | C13H11Br | 250mg
2-Methyl-5-bromobiphenyl | ≥95% | CAS 571903-41-8 | C13H11Br | 250mg
Aobchem 2-Fluoro-4-iodo-1 1 -biphenyl | 97% | CAS 56985-88-7 | C12H8FI | 1g
2-Fluoro-4-iodo-1 1 -biphenyl | 97% | CAS 56985-88-7 | C12H8FI | 1g
Aobchem 3-Bromo-4-chloro-1 1 -biphenyl | 95% | CAS 1537919-83-7 | C12H8BrCl | 250mg
3-Bromo-4-chloro-1 1 -biphenyl | 95% | CAS 1537919-83-7 | C12H8BrCl | 250mg
Aobchem 3-Bromo-4-chloro-1 1 -biphenyl | 95% | CAS 1537919-83-7 | C12H8BrCl | 1g
3-Bromo-4-chloro-1 1 -biphenyl | 95% | CAS 1537919-83-7 | C12H8BrCl | 1g
Aobchem 4-Bromo-2-chloro-1 1 -biphenyl | 97% | CAS 58775-86-3 | C12H8BrCl | 250mg
4-Bromo-2-chloro-1 1 -biphenyl | 97% | CAS 58775-86-3 | C12H8BrCl | 250mg
Aobchem 4-Bromo-3-fluoro-1 1 -biphenyl | 97% | CAS 150805-77-9 | C12H8BrF | 500mg
4-Bromo-3-fluoro-1 1 -biphenyl | 97% | CAS 150805-77-9 | C12H8BrF | 500mg
Aobchem 2-Methyl-5-bromobiphenyl | ≥95% | CAS 571903-41-8 | C13H11Br | 10g
2-Methyl-5-bromobiphenyl | ≥95% | CAS 571903-41-8 | C13H11Br | 10g
Aobchem 5-Bromo-2-fluorobiphenyl | ≥97% | CAS 1809168-63-5 | C12H8BrF | 1g
5-Bromo-2-fluorobiphenyl | ≥97% | CAS 1809168-63-5 | C12H8BrF | 1g
Aobchem 2-Bromo-4-fluoro-1 1 -biphenyl | ≥97% | CAS 53591-98-3 | C12H8BrF | 1g
2-Bromo-4-fluoro-1 1 -biphenyl | ≥97% | CAS 53591-98-3 | C12H8BrF | 1g
Aobchem 2-Biphenylboronic acid pinacol ester | ≥97% | CAS 914675-52-8 | C18H21BO2 | 5g
2-Biphenylboronic acid pinacol ester | ≥97% | CAS 914675-52-8 | C18H21BO2 | 5g