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Medchemexpress LLC (R)-eIF4A3-IN-2 | 2095484-82-3 | 602.70 | 50 MG
(R)-eIF4A3-IN-2 is a less active enantiomer of eIF4A3-IN-2. It is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM. This compound targets eukaryotic initiation factor (eIF) and is involved in the cell cycle/DNA damage pathway.
- Targets eukaryotic initiation factor (eIF)
- Involved in cell cycle/DNA damage pathway
- Powder storage: -20°C for 3 years, 4°C for 2 years
- In solvent storage: -80°C for 2 years, -20°C for 1 year
- Solubility in DMSO: 50 mg/mL (need ultrasonic)
- In vivo solubility: ≥ 2.5 mg/mL in 10% DMSO >> 40% PEG300 >> 5% Tween-80 >> 45% saline
- In vivo solubility: ≥ 2.5 mg/mL in 10% DMSO >> 90% corn oil
