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Organic compounds that consist of a phenol ring with a ciclohexane substitution; includes compounds in which the ciclohexane group has additional substitutions.
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
EW-7195 is a potent, selective ALK5 (TGFβR1) inhibitor for research use that blocks TGF-β1-induced Smad signaling, epithelial-to-mesenchymal transition, and metastatic progression in preclinical studies. It provides low-nanomolar potency and is supplied with high purity for laboratory assays.
Potent ALK5 inhibition with low-nanomolar IC50.
High selectivity over related kinases, >300-fold versus p38α.
Blocks TGF-β1-induced Smad signaling and epithelial-to-mesenchymal transition.
Demonstrated anti-metastasis activity in preclinical models.
High purity suitable for research applications.
Soluble in DMSO for assay preparation.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More