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Organic compounds that consist of a phenol ring with a ciclohexane substitution; includes compounds in which the ciclohexane group has additional substitutions.
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Estradiol-d4 is the deuterium labeled Estradiol. Estradiol is a steroid sex hormone vital to the maintenance of fertility and secondary sexual characteristics in females. It upregulates IL-6 expression through the estrogen receptor beta (ERβ) pathway.
Used as a tracer
Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Incorporates stable heavy isotopes of hydrogen, carbon, and other elements
Deuteration affects the pharmacokinetic and metabolic profiles of drugs
Applicable in cancer research, metabolic or endocrine disease, and endocrinology
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Imifoplatin (PT-112) is a platinum-based active molecule, categorized within the phosphaplatins family. It is known for its ability to induce apoptosis and demonstrates significant antitumor activity. This compound has been investigated for its potential in treating various cancers, showing promising results in both *in vitro* and *in vivo* studies, particularly in inhibiting proliferation and inducing apoptosis in cancer cell lines.
Induces apoptosis.
Exhibits antitumor activity.
Shows dose-dependent proliferation inhibition in cancer cells.
Significantly increases mitochondrial reactive oxygen species (mtROS).
Demonstrates potent antitumor immune effects in xenograft models.
Shows synergistic antitumor effects when combined with immune checkpoint blockers.
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Mauritianin is an orally active kaempferol glycoside isolated from the flowers and leaves of Acalypha indica. It is reported to inhibit topoisomerase I and is provided as a high-purity research reagent with supporting product documentation and safety data.
Orally active kaempferol glycoside with reported biological activity.
High purity: 99.8% as listed by the supplier.
Chemical formula C33H40O19 and molecular weight 740.66 g·mol⁻¹.
Supplied as a solid in small research quantities (example: 10 mg).
Product data sheet and safety data sheet available for handling and characterization.
Suitable for research into flavonoid bioactivity and topoisomerase-related mechanisms.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
Parishin is a phenolic glucoside isolated from Gastrodia elata that exhibits anti-aging activity in yeast via modulation of the Sir2/Uth1/TOR signaling pathway. It is supplied as a high-purity solid with recommended solvent formulations and storage conditions for research applications.
High purity (98.92%)
Off-white to light yellow solid
Available as solid and as 10 mM DMSO solution for in vitro use