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Medchemexpress LLC Imifoplatin | 1339960-28-9 | 95.0% | 485.23 | 50 MG
SDP

Catalog No. 5000343726
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Imifoplatin (PT-112) is a platinum-based active molecule and a member of the phosphaplatins family. Imifoplatin can induce Apoptosis and exhibits antitumor activity.

  • Inhibits proliferation in HCT116 cells.
  • Induces apoptosis in HCT116 cells.
  • Inhibits proliferation in CT26 cells.
  • Shows selectivity, strongly inhibiting glycolytic tumor cells with mtDNA mutations.
  • Increases mtROS, especially in glycolytic L929dt and Cybrid cells.
  • Demonstrates potent antitumor immune effects in the CT26 xenograft model.
  • Shows synergistic antitumor effects in the MC38 xenograft model, especially with PD-1 blockade.

Catalog No. 50-003-43726 Supplier Medchemexpress LLC Supplier No. HY10914650MG
May include imposed supplier surcharges.
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Imifoplatin (PT-112) is a platinum-based active molecule and a member of the phosphaplatins family. Imifoplatin can induce Apoptosis and exhibits antitumor activity.

  • Inhibits proliferation in HCT116 cells.
  • Induces apoptosis in HCT116 cells.
  • Inhibits proliferation in CT26 cells.
  • Shows selectivity, strongly inhibiting glycolytic tumor cells with mtDNA mutations.
  • Increases mtROS, especially in glycolytic L929dt and Cybrid cells.
  • Demonstrates potent antitumor immune effects in the CT26 xenograft model.
  • Shows synergistic antitumor effects in the MC38 xenograft model, especially with PD-1 blockade.

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