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TD52 dihydrochloride is a research-grade small-molecule inhibitor of cancerous inhibitor of protein phosphatase 2A (CIP2A). An Erlotinib derivative, it is orally active and induces apoptosis in triple-negative breast cancer cells by modulating the CIP2A/PP2A/p-Akt signaling pathway. Supplied as the dihydrochloride salt, the compound includes an alkyne group that enables click-chemistry applications.
High purity suitable for research applications (99.6%).
Available in small research pack sizes, including 5 mg.
Supplied as solid powder and as a 10 mM solution in DMSO.
Targeted for oncology and cell-signaling studies involving CIP2A/PP2A.
Compatible with copper-catalyzed azide-alkyne cycloaddition reactions.
Molecular formula C24H18Cl2N4; molecular weight 433.33 g/mol.
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