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SB-265610 is a selective, competitive, nonpeptide, allosteric antagonist of the CXCR2 chemokine receptor used as a research reagent to study neutrophil chemotaxis and CXCR2-mediated signaling. It inhibits CINC-1-induced calcium mobilization (IC50 3.7 nM) and neutrophil chemotaxis (IC50 70 nM).
Selective CXCR2 antagonist for receptor pharmacology studies.
Reported low-nanomolar potency for calcium mobilization assays.
Suitable for in vitro chemotaxis and signaling experiments.
Supplied as a small-molecule solid for formulation or dosing control.
Characterized by published analytical data and CAS registration for traceability.
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