Phenoxy compounds

Medchemexpress LLC HY-10029 10mg Medchemexpress, Nutlin-3a CAS:675576-98-4 Purity:>98%

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Medchemexpress, HY-10029 10mg Nutlin-3a CAS:675576-98-4 Nutlin-3a, an active enantiomer of Nutlin-3, is a potent murine double minute (MDM2) inhibitor (IC50=90 nM). Nutlin-3a inhibits MDM2-p53 interactions and stabilizes the p53 protein, and induces cell autophagy and apoptosis. Nutlin-3a has the potential for the study of TP53 wild-type ovarian carcinomas[2]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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Medchemexpress LLC HY-16562 100mg Medchemexpress, Irinotecan CAS:97682-44-5 Purity:>98%

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Medchemexpress, HY-16562 100mg Irinotecan CAS:97682-44-5 Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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Medchemexpress LLC HY-13757 5g Medchemexpress, Tamoxifen (Citrate) CAS:54965-24-1 Purity:>98%

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Medchemexpress, HY-13757 5g Tamoxifen (Citrate) CAS:54965-24-1 Tamoxifen Citrate (ICI 46474) is an orally active, selective estrogen receptor modulator (SERM) which blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells[2][3].Tamoxifen Citrate is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity. Tamoxifen Citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC50 of 0.1 µM and 1.8 µM, respectively[5]. Tamoxifen Citrate activates autophagy and induces apoptosis[4]. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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Medchemexpress LLC HY-13992 1mg Medchemexpress, AP20187 CAS:195514-80-8 Purity:>98%

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Medchemexpress, HY-13992 1mg AP20187 CAS:195514-80-8 AP20187 (B/B Homodimerizer) is a cell-permeable ligand used to dimerize FK506-binding protein (FKBP) fusion proteins and initiate biological signaling cascades and gene expression or disrupt protein-protein interactions. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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Medchemexpress LLC HY-12067 5mg Medchemexpress, R406 CAS:841290-81-1 Purity:>98%

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Medchemexpress, HY-12067 5mg R406 CAS:841290-81-1 R406 is a competitive Syk inhibitor for ATP binding with a Ki of 30 nM, potently inhibits Syk kinase activity in vitro with an IC50 of 41 nM, measured at an ATP concentration corresponding to its Km value. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

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Sigma Aldrich Fine Chemicals Biosciences Roflumilast >=98% (HPLC) | 162401-32-3 | MFCD00938270 | 10MG

Roflumilast >=98% (HPLC) | Purity: >=98% (HPLC) | Mol Wt: 403.21 | 162401-32-3 | MFCD00938270 | 10MG

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Medchemexpress LLC Eliglustat-d4 | 98.0% | 408.57 | 5 MG

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Eliglustat-d4 is the deuterium labeled Eliglustat. Eliglustat is a specific, potent, and orally active glucocerebroside synthase inhibitor with an IC50 of 24 nM. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

• It is the deuterium labeled version of Eliglustat.
• It can be used as a tracer.
• It can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
• Deuteration has potential to affect the pharmacokinetic and metabolic profiles of drugs.

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