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Filtered Search Results
eMolecules 1000998-59-3 | Medchem Express | BMS-687453 | 5mg | 446259008 | HY-10678 | MFCD18251482 | 444.87 | C22H21ClN2O6
Medchem Express | BMS-820132 | 5mg | 722714370 | HY-144289 | 1001419-18-6 | 572.559 | C26H33N6O7P
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Selleck Chemical LLC Telaglenastat
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Telaglenastat (CB-839) is a potent selective and orally bioavailable glutaminase inhibitor with IC50 of 24 nM for recombinant human GAC CB-839(Telaglenastat) inudces autophagy and has antitumor activity Phase 1
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eMolecules 1488363-78-5 | Medchem Express | Adomeglivant | 5mg | 446270500 | HY-19904 | MFCD30343860 | 555.638 | C32H36F3NO4
Ambeed | Sodium 23-dimercaptopropane-1-sulfonate hydrate | 1g | 513350172 | A599319 | 207233-91-8 | MFCD00149543 | 228.270 | C3H9NaO4S3
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Medchemexpress LLC Dihydrodiol-ibrutinib | 1654820-87-7 | 99.9% | 474.51 g/mol | C25H26N6O4 | 5 MG
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Dihydrodiol-ibrutinib is a dihydrodiol active metabolite of ibrutinib that retains BTK inhibitory activity at a lower potency than the parent compound. Supplied as a white to off-white solid for laboratory research use, it is suitable for in vitro assays and formulation studies and can be prepared in common solvents for dosing formulations.
- Active metabolite with measurable BTK inhibition (~15x lower than parent)
- High reported purity, suitable for research applications
- White to off-white solid for convenient handling
- Soluble in DMSO and compatible with multiple in vivo formulation vehicles
- Stable under recommended cold storage conditions for extended periods
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Medchemexpress LLC Mps1-IN-3 hydrochloride | 2989453-29-2 | 98.0% | 574.09 | C26H32ClN7O4S | 25MG
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Mps1-IN-3 hydrochloride is the hydrochloride salt of a potent and selective MPS1 (TTK) kinase inhibitor (reported IC50 ≈ 50 nM) provided for research use. The compound is supplied as a solid with high purity, chemical formula C26H32ClN7O4S, and molecular weight 574.09 g/mol; it is commonly packaged in small quantities for in vitro biochemical and cell-based studies.
- Potent MPS1 kinase inhibitor with reported IC50 ≈ 50 nM.
- High purity solid suitable for research applications.
- Chemical formula C26H32ClN7O4S and molecular weight 574.09 g/mol.
- Hydrochloride salt form to aid solubility for assays.
- Packaged in small quantities for laboratory testing and method development.
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Medchemexpress LLC GSK2945 hydrochloride | 98.5% | 457.80 | 100 MG
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GSK2945 hydrochloride is a class of tertiary amine, and is a highly specific Rev-erbα/REV-ERBα (mouse/human reverse erythroblastosis virus α) antagonist with EC50s of 21.5 μM and 20.8 μM, respectively. It enhances cholesterol 7α-hydroxylase (CYP7A1) level and cholesterol metabolism.
- Dose-dependently enhances the transcriptional activity of Rev-erbα and a Bmal1 (a target gene of REV-ERBs) luciferase reporter (EC50 of 2.05 μM).
- Treatment (20 μM; 12 hours and 24 hours; mouse and human primary hepatocytes) increases levels of Cyp7a1/CYP7A1 in mouse and human primary hepatocytes.
- Treatment (20 μM) also increases Lrh-1/LRH-1 (a known hepatic activator of Cyp7a1/CYP7A1) mRNA and protein.
- Treatment (0-10 mg/kg; intraperitoneal injection; twice every day; for 7 days; male C57BL/6 mice) increases hepatic mouse cholesterol 7α-hydroxylase (Cyp7a1) level and lowers plasma cholesterol in wild-type mice.
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Selleck Chemical LLC Naproxen S5177-25mg
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Naproxen is an anti-inflammatory agent with analgesic and antipyretic properties It is a nonselective inhibitor of COX-1 and COX-2
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eMolecules 1633044-56-0 | Medchem Express | FIIN-2 | 5mg | 446269119 | HY-18602 | MFCD28386553 | 634.741 | C35H38N8O4
Medchem Express | ARD-69 | 1mg | 761040911 | HY-114402 | 2316837-10-0 | 1129.830 | C62H74ClFN8O7S
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eMolecules 1005780-62-0 | Medchem Express | TAK-593 | 5mg | 446265822 | HY-15506 | MFCD23160045 | 445.483 | C23H23N7O3
ChemScene | 4-Chloro-2-methoxybenzonitrile | 1g | 572194458 | CS-0115635 | 100960-68-7 | MFCD09865166 | 167.590 | C8H6ClNO
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eMolecules 2558205-28-8 | Medchem Express | AkaLumine (hydrochloride) | 5mg | 482204028 | HY-112641A | 338.85 | C16H19ClN2O2S
ChemScene | 3-(4-Fluorophenyl)isoxazole-5-carboxylic acid | 250mg | 632276395 | CS-0029798 | 618383-48-5 | MFCD05150725 | 207.160 | C10H6FNO3
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eMolecules 938-73-8 | 2-Ethoxybenzamide | Oakwood Chemicals | MFCD00007977 | 165.192 | C9H11NO2 | 97.000 | CCOc1ccccc1C(N)=O | 5g | 480149412
2-Ethoxybenzamide | Oakwood Chemicals | 938-73-8 | MFCD00007977 | 165.192 | C9H11NO2 | 97.000 | CCOc1ccccc1C(N)=O | 5g | 480149412
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Selleck Chemical LLC Dofetilide S1658-200mg
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Dofetilide (UK-68798) is a selective potassium channel ((hERG)) blocker used as a Class III antiarrhythmic drug
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Selleck Chemical LLC 4.4-Dimethoxybenzil S5310-25mg
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4 4 -Dimethoxybenzil (p-Anisil) is a biochemical that has been reported to have mesomorphic properties of a substituted bis(dithiolene)nickel complex derived from 4 4 -dimethoxybenzil
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Medchemexpress LLC HY-100220 2mg Medchemexpress, GSK6853 CAS:1910124-24-1 Purity:>98%
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Medchemexpress, HY-100220 2mg GSK6853 CAS:1910124-24-1 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC HY-15079 5mg Medchemexpress, Talampanel CAS:161832-65-1 Purity:>98%
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Medchemexpress, HY-15079 5mg Talampanel CAS:161832-65-1 Talampanel (LY300164) is an orally and selective α-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor antagonis with anti-seizure activity. Talampanel (IVAX) has neuroprotective effects in rodent stroke models. Talampanel attenuates caspase-3 dependent apoptosis in mouse brain. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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