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Filtered Search Results
Medchemexpress LLC SRC INHIBITOR 1 5MG
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Src Inhibitor 1 is a potent, ATP-competitive and selective dual site Src tyrosine kinase inhibitor with IC50 values of 44 nM for Src and 88nM for Lck.CAS No. : 179248-59-0
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Medchemexpress LLC (±)-Vesamicol hydrochloride | 120447-62-3 | 99.8% | 5 MG
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(±)-Vesamicol hydrochloride | 120447-62-3 | 99.8% | 5 MG
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eMolecules 103860-60-2 | 2,3-Dihydroxynaphthalene-1,4-dicarbaldehyde | MFCD09800457 | 100mg
Medchem Express | Terevalefim | 5mg | 665626281 | HY-137455 | 1070881-42-3 | 176.240 | C9H8N2S
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Medchemexpress LLC HY-17449 50mg , Fosbretabulin (disodium) CA 4DP;CA 4P;Combretastatin A4 disodium phosphate CAS:168555-66-6 Purity:98%
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Medchemexpress, HY-17449 50mg Fosbretabulin (disodium) CA 4DP;CA 4P;Combretastatin A4 disodium phosphate CAS:168555-66-6 Formula:C18H19Na2O8P Purity:98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC Mcoppb (trihydrochloride) | 1108147-88-1 | 100.0% | 50 MG
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MCOPPB trihydrochloride is a nonpeptide nociceptin/orphanin FQ peptide (NOP)-receptor agonist, exhibiting a pKi of 10.07 for the human NOP receptor. It shows weaker activity at other opioid receptors. This compound is the trihydrochloride form of MCOPPB, making it suitable for various research applications.
- Acts as a nociceptin receptor agonist
- Demonstrates high purity of 99.98%
- Stable under recommended storage conditions
- Soluble in DMSO (100 mg/mL) for in vitro applications
- Can be formulated for in vivo studies with clear solutions
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Medchemexpress LLC Dm4-sme | 796073-68-2 | 98.0% | 826.46 g/mol | C39H56ClN3O10S2 | 10 MG
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DM4-SMe is a cytotoxic maytansinoid metabolite and microtubule/tubulin inhibitor used as an antibody-drug conjugate (ADC) payload in laboratory research. Supplied as a powder in small mass quantities, it is intended for in vitro and conjugation studies.
- Cytotoxic maytansinoid metabolite and tubulin inhibitor.
- Suitable as an ADC payload or for conjugation studies.
- Supplied as a powder in small mass quantities for research use.
- CAS number 796073-68-2 for unambiguous identification.
- Reported molecular weight 826.46 g/mol and formula C39H56ClN3O10S2.
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Medchemexpress LLC HY-19947 5mg Medchemexpress, PF-06291874 CAS:1393124-08-7 Purity:>98%
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Medchemexpress, HY-19947 5mg PF-06291874 CAS:1393124-08-7 PF-06291874 is a highly potent, non-peptide and orally active glucagon receptor antagonist. PF-06291874 is under the study for type 2 diabetes mellitus (T2DM). Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC AN3199 | 1187187-10-5 | 99.7% | 327.14 | 100 MG
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AN3199 is a potent PDE4 inhibitor with an IC50 of 94.5 nM. It is designed for research into inflammation-associated diseases such as asthma and chronic obstructive pulmonary disease (COPD).
- Potent PDE4 inhibitor (IC50 of 94.5 nM)
- Suitable for research on inflammation-associated diseases
- Relevant for studies on asthma and chronic obstructive pulmonary disease (COPD)
- Exhibits rapid conversion to an acid in mouse plasma
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Medchemexpress LLC Pramocaine hydrochloride | 637-58-1 | 99.74% | 500 MG
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Pramocaine hydrochloride is an antipruritic agent that decreases the permeability of neuronal membranes to sodium ions, thereby blocking both the initiation and conduction of nerve impulses. This product is for research use only and is not sold to patients.
- Decreases the permeability of neuronal membranes to sodium ions, blocking the initiation and conduction of nerve impulses.
- Available with a purity of 99.74%.
- Offers solubility in both DMSO and H2O, with detailed preparation instructions for stock solutions.
- Provides specific protocols for in vivo dissolution using various co-solvents such as DMSO, PEG300, Tween-80, Saline, SBE-β-CD, and Corn Oil.
- Primarily intended as a chemical reagent for research purposes.
- Reference compound.
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eMolecules 66280-25-9 | (6R,7S,12AS)-1,2,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrodibenzo[a,c][8]annulene-3,10-diol | MFCD29048562 | 5mg
Ambeed | (6R,7S,12AS)-1,2,11,12-tetramethoxy-6,7-dimethyl-5,6,7,8-tetrahydrodibenzo[a,c][8]annulene-3,10-diol | 5mg | 598442325 | A361884 | 66280-25-9 | MFCD29048562 | 388.460 | C22H28O6
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Medchemexpress LLC AMG 579 | 1227067-61-9 | 99.0% | 100 MG
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AMG 579 is a potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A) with an IC50 of 0.1 nM. It is intended for research use only. In vivo, it significantly reduced PCP-induced behavior in rats over a 2-hour period with a minimum effective dose of 0.3 mg/kg, and in dogs, it exhibits a superior oral bioavailability of 72%.
- Potent, selective, and efficacious inhibitor of phosphodiesterase 10A (PDE10A)
- Has an IC50 of 0.1 nM
- Significantly reduces PCP-induced behavior in rats
- Exhibits superior oral bioavailability in dogs (72%)
- For research use only
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Medchemexpress LLC Zingiberen newsaponin | 91653-50-8 | 99.7% | 1047.18 g/mol | C51H82O22 | 10 MG
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Zingiberen newsaponin is an orally active steroid saponin used in preclinical research with reported anticancer and neuroprotective activities. It is provided as a solid for laboratory studies and is intended for research use only.
- Orally active steroid saponin with reported in vitro and in vivo activity.
- Exerts anti-hepatocellular carcinoma effects by inhibiting autophagy and the AKR1C1/JAK2/STAT3 pathway.
- Activates oxidative stress and mitochondrial pathways, promoting cancer cell apoptosis.
- Alleviates cerebral ischemia-reperfusion injury and reduces pro-inflammatory cytokines.
- Enhances antioxidant enzyme activity and protects nerve cells.
- Solid form; white to off-white appearance; store sealed away from moisture and light.
- Analytical purity reported at 99.68%.
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Medchemexpress LLC KRAS inhibitor-10 | 2578876-75-0 | 99.9% | 519.63 | 100 MG
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KRAS inhibitor-10 selectively and effectively inhibits RAS proteins, particularly KRAS proteins. It is an orally active anti-cancer agent and can be used for cancer research, including pancreatic cancer, breast cancer, multiple myeloma, leukemia, and lung cancer.
- Selectively inhibits RAS proteins, particularly KRAS proteins.
- Orally active anti-cancer agent.
- Demonstrates antiproliferative effects in KRas mutant tumor cells.
- Shows significant oral anti-tumor activities in vivo.
- Soluble in DMSO: 100 mg/mL.
- Powder storage: -20°C for 3 years, 4°C for 2 years.
- In solvent storage: -80°C for 6 months, -20°C for 1 month.
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Medchemexpress LLC AMG 837 calcium hydrate | 1259389-38-2 | 99.0% | 455.45 | 100 MG
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AMG 837 calcium hydrate is a potent, orally bioavailable, and partial agonist of GPR40/FFA1. It inhibits specific [3H]AMG 837 binding at the human FFA1 receptor with a pIC50 of 8.13. AMG 837 calcium hydrate can enhance insulin secretion and lower glucose levels in rodents. It is also a click chemistry reagent, containing an Alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- Potent, orally bioavailable, and partial agonist of GPR40/FFA1.
- Inhibits specific [3H]AMG 837 binding at the human FFA1 receptor with a pIC50 of 8.13.
- Enhances insulin secretion and lowers glucose levels in rodents.
- Click chemistry reagent with an Alkyne group for CuAAc reactions.
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Medchemexpress LLC 2-(4-Chloro-phenoxy)-phenylacetic acid | 25563-04-6 | 99.6% | 262.69 | 100 MG
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2-(4-Chloro-phenoxy)-phenylacetic acid is a drug intermediate used for the synthesis of various active compounds. This product is intended for research use only, and MedChemExpress does not sell to patients.
- Suitable for high-speed applications
- Room temperature shipping in continental US
- Storage in powder form: -20°C for 3 years, 4°C for 2 years
- Storage in solvent: -80°C for 6 months, -20°C for 1 month
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