Phenylhydrazines
Medchemexpress LLC Lomefloxacin (hydrochloride) | 98079-52-8 | 100.0% | 1 G
Lomefloxacin hydrochloride (NY-198 hydrochloride) is an orally active difluoroquinolone antibiotic that prevents DNA supercoiling and replication by inhibiting bacterial topoisomerase II. It induces ROS production and Apoptosis, and exhibits broad-spectrum bactericidal activity against Gram-positive and Gram-negative bacteria. Lomefloxacin hydrochloride also demonstrates anticancer effects against melanoma. It can be used in the study of systemic bacterial infections (such as Salmonella typhimurium infections), skin, and melanoma.
- Orally active difluoroquinolone antibiotic
- Inhibits bacterial topoisomerase II to prevent DNA supercoiling and replication
- Induces ROS production and apoptosis
- Exhibits broad-spectrum bactericidal activity against Gram-positive and Gram-negative bacteria
- Demonstrates anticancer effects against melanoma
- Used in the study of systemic bacterial infections, skin, and melanoma
Medchemexpress LLC Methacycline hydrochloride | 3963-95-9 | 99.3% | 1 ML
Methacycline hydrochloride is a tetracycline antibiotic that inhibits bacterial protein synthesis and is a potent inhibitor of epithelial-mesenchymal transition (EMT). It blocks EMT in vitro and fibrogenesis in vivo without directly affecting TGF-β1 Smad signaling, demonstrating potential relevance for pulmonary fibrosis.
- Inhibits bacterial protein synthesis
- Potent inhibitor of epithelial-mesenchymal transition (EMT)
- Blocks EMT in vitro and fibrogenesis in vivo
- Suggests potential for treating pulmonary fibrosis
- Inhibits TGF-β1-induced non-Smad pathways
Medchemexpress LLC Pheniprazine hydrochloride | 66-05-7 | 98.7% | 186.68 g·mol⁻¹ | C9H15ClN2 | 50 MG
Pheniprazine hydrochloride is the hydrochloride salt of pheniprazine, an irreversible, nonselective monoamine oxidase (MAOI) inhibitor supplied for research use in biochemical and pharmacological studies of monoamine systems and depression.
- Irreversible, nonselective monoamine oxidase inhibitor.
- Useful research tool for studies of depression and monoaminergic signaling.
- Supplied as a white to off-white solid.
- Typical purity about 98.7%.
- Available in small research quantities, for example 50 mg.
- Store solid at 4°C, sealed and away from moisture; in solution store at -80°C for long-term storage.
Medchemexpress LLC CDK4/6-IN-15 (hydrochloride) | 2078047-99-9 | MFCD09904297 | 99.3% | C21H28ClFN8S | 100 MG
CDK4/6-IN-15 (hydrochloride) is an orally active and selective CDK4/6 inhibitor that potently inhibits cancer cell growth. It arrests the cell cycle at the G1 phase and suppresses retinoblastoma tumour suppressor protein (Rb) phosphorylation at S780 and E2 factor (E2F)-regulated gene expression.
- Potently inhibits cancer cell growth
- Arrests the cell cycle at G1 phase
- Suppresses retinoblastoma tumour suppressor protein (Rb) phosphorylation at S780
- Suppresses E2 factor (E2F)-regulated gene expression