Phenylmethylamines
Apexbio Technology LLC Ambroxol HCl 23828-92-4 50mg
Ambroxol HCl (CAS 23828-92-4) is a small molecule known for its inhibitory activity on neuronal voltage-gated sodium (Na ) channels It exhibits potent blockade of both tetrodotoxin-resistant (TTX-R) and tetrodotoxin-sensitive (TTX-S) Na currents with half-maximal inhibitory concentrations (IC50) of 35 2 M and 22 5 M for tonic and phasic block of TTX-R currents respectively and 100 M for TTX-S currents These properties position Ambroxol HCl as a valuable tool for investigating sodium channel function and pain signaling pathways and support its evaluation in clinical research settings
Medchemexpress LLC Ambroxol hydrochloride | 23828-92-4 | 99.96% | 100 MG
Ambroxol hydrochloride (NA-872 hydrochloride) is an active metabolite of Bromhexine, known for its potent expectorant effects. It acts as a glucocerebrosidase (GCase) chaperone, increasing glucocerebrosidase activity. This compound also induces lung autophagy and shows potential for research in Parkinson's disease and neuronopathic Gaucher disease.
- Potent expectorant effects.
- Increases glucocerebrosidase activity.
- Induces lung autophagy.
- Potential for Parkinson's disease research.
- Potential for neuronopathic Gaucher disease research.